Evidence map›Paper›PMID 25067957›Full record

ArticleDiabetes management (London, England)2013

Targeting sirtuins for the treatment of diabetes.

Frank K Huynh, Kathleen A Hershberger, Matthew D Hirschey

Open access · greenAbstract read
In one paragraph

Article in Diabetes management (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Molecular basis of ageing in chronic metabolic diseases.Journal of endocrinological investigation · 2020
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Metabolic pathways at the crossroads of diabetes and inborn errors.Journal of inherited metabolic disease · 2018
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Sources and implications of NADH/NAD(+) redox imbalance in diabetes and its complications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Frank K HuynhSarah W Stedman Nutrition & Metabolism Center, Duke University Medical Center, Durham, NC 27704, USA.
Kathleen A HershbergerSarah W Stedman Nutrition & Metabolism Center, Duke University Medical Center, Durham, NC 27704, USA ; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.
Matthew D HirscheySarah W Stedman Nutrition & Metabolism Center, Duke University Medical Center, Durham, NC 27704, USA ; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA ; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Duke University · US

Funding

Studies on the Mechanisms by which SIRT5 Regulates Aging and DiseaseR01AG045351 · NIA · DUKE UNIVERSITY · PI HIRSCHEY, MATTHEW D · 2014 to 2023
$4.4M
Ethanol-induced Protein Acylation Regulates MetabolismR01AA022146 · NIAAA · DUKE UNIVERSITY · PI FRITZ, KRISTOFER S, HIRSCHEY, MATTHEW D · 2013 to 2017
$2.3M
NIAAA NIH HHS R01 AA022146NIA NIH HHS R01 AG045351
6 · The paper itself

Abstract

Sirtuins are a class of NAD

Identifiers

PMID25067957
PMCPMC4110209
OpenAlexW1985955137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.