Evidence map›Paper›PMID 25067942›Full record

ReviewChinese medicine2014

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.

Kam Lok Wong, Ricky Ngok Shun Wong, Liang Zhang, Wing Keung Liu, Tzi Bun Ng, Pang Chui Shaw, Philip Chi Lip Kwok, Yau Ming Lai, Zhang Jin Zhang, Yanbo Zhang and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Microorganisms · 2022
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Herb Formula ZhenRongDan Balances Sex Hormones, Modulates Organ Atrophy, and Restores EREvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  11. Small Peptides Compound Isolated fromEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Kam Lok WongSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Ricky Ngok Shun WongDepartment of Biology, Faculty of Science, Hong Kong Baptist University, Hong Kong Special Administrative Region, China.
Liang ZhangSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Wing Keung LiuSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
Tzi Bun NgSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
Pang Chui ShawSchool of Life Sciences and Centre for Protein Science and Crystallography, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region, China.
Philip Chi Lip KwokDepartment of Pharmacology & Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Yau Ming LaiDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, China.
Zhang Jin ZhangSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Yanbo ZhangSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Yao TongSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Ho-Pan CheungSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Jia LuSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Stephen Cho Wing SzeSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Chinese University of Hong Kong · CNUniversity of Hong Kong · HKHong Kong Baptist University · HKHong Kong Polytechnic University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

Identifiers

PMID25067942
PMCPMC4110622
OpenAlexW2108794803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.