Evidence map›Paper›PMID 25066537›Full record

ArticlePsychological medicine2015

Natural course of cannabis use disorders.

R F Farmer, D B Kosty, J R Seeley, S C Duncan, M T Lynskey, P Rohde, D N Klein, P M Lewinsohn

Abstract read
In one paragraph

Article in Psychological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Sex differences in the relationship between cannabis use motives and cannabis craving in daily life in emerging adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Article
  8. Mechanisms of cannabinoid tolerance.Biochemical pharmacology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Adult Psychiatric, Substance, and Functional Outcomes of Different Definitions of Early Cannabis Use.Journal of the American Academy of Child and Adolescent Psychiatry · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Gender Norms, Roles and Relations and Cannabis-Use Patterns: A Scoping Review.International journal of environmental research and public health · 2020
    Article
  19. Sex and Gender Interactions on the Use and Impact of Recreational Cannabis.International journal of environmental research and public health · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R F FarmerOregon Research Institute,Eugene, OR 97403,USA.
D B KostyOregon Research Institute,Eugene, OR 97403,USA.
J R SeeleyOregon Research Institute,Eugene, OR 97403,USA.
S C DuncanOregon Research Institute,Eugene, OR 97403,USA.
M T LynskeyAddictions Department,Institute of Psychiatry, King's College London,London,UK.
P RohdeOregon Research Institute,Eugene, OR 97403,USA.
D N KleinDepartment of Psychology,Stony Brook University,Stony Brook, NY,USA.
P M LewinsohnOregon Research Institute,Eugene, OR 97403,USA.

Funding

Risk for Substance Use Disorders and Comorbid ConditionsR01DA012951 · NIDA · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 2000 to 2004
$3.3M
Natural Course of Cannabis Use Disorders from Childhood Through Early AdulthoodR01DA032659 · NIDA · OREGON RESEARCH INSTITUTE · PI FARMER, RICHARD FRANCIS, SEELEY, JOHN R · 2012 to 2013
$458k
NATURAL HISTORY OF DEPRESSION IN ADOLESCENTSR01MH050522 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1993 to 2001
$121k
ADOLESCENT DEPRESSION: PREVALENCE &PSYCHOSOCIAL ASPECTSR01MH040501 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1986 to 1990
–
NIDA NIH HHS DA032659NIDA NIH HHS DA12951NIDA NIH HHS R01 DA012951NIDA NIH HHS R01 DA032659NIMH NIH HHS R01 MH040501NIMH NIH HHS R01 MH050522
6 · The paper itself

Abstract

backgroundDespite its importance as a public health concern, relatively little is known about the natural course of cannabis use disorders (CUDs). The primary objective of this research was to provide descriptive data on the onset, recovery and recurrence functions of CUDs during the high-risk periods of adolescence, emerging adulthood and young adulthood based on data from a large prospective community sample.

methodProbands (n = 816) from the Oregon Adolescent Depression Project (OADP) participated in four diagnostic assessments (T1-T4) between the ages of 16 and 30 years, during which current and past CUDs were assessed.

resultsThe weighted lifetime prevalence of CUDs was 19.1% with an average onset age of 18.6 years. Although gender was not significantly related to the age of initial CUD onset, men were more likely to be diagnosed with a lifetime CUD. Of those diagnosed with a CUD episode, 81.8% eventually achieved recovery during the study period. Women achieved recovery significantly more quickly than men. The recurrence rate (27.7%) was relatively modest, and most likely to occur within the first 36 months following the offset of the first CUD episode. CUD recurrence was uncommon after 72 months of remission and recovery.

conclusionsCUDs are relatively common, affecting about one out of five persons in the OADP sample prior to the age of 30 years. Eventual recovery from index CUD episodes is the norm, although about 30% of those with a CUD exhibit a generally persistent pattern of problematic use extending 7 years or longer.

Indexed as

AdolescentAdultAge of OnsetFemaleHumansIncidenceInterviews as TopicMaleMarijuana AbuseOregonPrevalenceProportional Hazards ModelsRecurrenceSex DistributionTreatment OutcomeYoung Adult

Identifiers

PMID25066537
PMCPMC4229487

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.