Evidence map›Paper›PMID 25066001›Full record

ArticlePsychological medicine2014

Associations of cannabis and cigarette use with psychotic experiences at age 18: findings from the Avon Longitudinal Study of Parents and Children.

S H Gage, M Hickman, J Heron, M R Munafò, G Lewis, J Macleod, S Zammit

Open access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
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  19. A Twin Study on the Association Between Psychotic Experiences and Tobacco Use During Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2019
    Article
  20. The relationship between nicotine and psychosis.Therapeutic advances in psychopharmacology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S H GageSchool of Social and Community Medicine,University of Bristol,UK.
M HickmanSchool of Social and Community Medicine,University of Bristol,UK.
J HeronSchool of Social and Community Medicine,University of Bristol,UK.
M R MunafòMRC Integrative Epidemiology Unit,University of Bristol,UK.
G LewisSchool of Social and Community Medicine,University of Bristol,UK.
J MacleodSchool of Social and Community Medicine,University of Bristol,UK.
S ZammitInstitute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics,Cardiff University,UK.
University of Bristol · GBCardiff University · GBMRC Epidemiology Unit · GB

Funding

Medical Research Council 74882Medical Research Council G0701503Medical Research Council G0800612Medical Research Council G0801418Medical Research Council G0802736Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/6Medical Research Council MR/K023195/1Medical Research Council MR/K023233/1Medical Research Council MR/L010305/1Wellcome Trust 076467Wellcome Trust 102215
6 · The paper itself

Abstract

backgroundA clearer understanding of the basis for the association between cannabis use and psychotic experiences (PEs) is required. Our aim was to examine the extent to which associations between cannabis and cigarette use and PEs are due to confounding.

methodA cohort study of 1756 adolescents with data on cannabis use, cigarette use and PEs.

resultsCannabis use and cigarette use at age 16 were both associated, to a similar degree, with PEs at age 18 [odds ratio (OR) 1.48, 95% confidence interval (CI) 1.18-1.86 for cannabis and OR 1.61, 95% CI 1.31-1.98 for cigarettes]. Adjustment for cigarette smoking frequency (OR 1.27, 95% CI 0.91-1.76) or other illicit drug use (OR 1.25, 95% CI 0.91-1.73) substantially attenuated the relationship between cannabis and PEs. The attenuation was to a lesser degree when cannabis use was adjusted for in the cigarette PE association (OR 1.42, 95% CI 1.05-1.92). However, almost all of the participants used cannabis with tobacco, including those who classed themselves as non-cigarette smokers.

conclusionsTeasing out the effects of cannabis from tobacco is highly complex and may not have been dealt with adequately in studies to date, including this one. Complementary methods are required to robustly examine the independent effects of cannabis, tobacco and other illicit drugs on PEs.

Indexed as

AdolescentCohort StudiesComorbidityFemaleHumansLongitudinal StudiesMaleMarijuana SmokingOdds RatioParentsPsychotic DisordersSmokingSurveys and QuestionnairesUnited Kingdom

Identifiers

PMID25066001
PMCPMC4255321
OpenAlexW2158274508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.