Evidence map›Paper›PMID 25064850›Full record

ArticleNature neuroscience2014

Cerebellum involvement in cortical sensorimotor circuits for the control of voluntary movements.

Rémi D Proville, Maria Spolidoro, Nicolas Guyon, Guillaume P Dugué, Fekrije Selimi, Philippe Isope, Daniela Popa, Clément Léna

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed, 1 synthesis or guideline pooled it, 273 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Disrupted Brain Connectivity in Newborns Following Antenatal Opioid Exposure.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Synergistic Reinforcement Learning by Cooperation of the Cerebellum and Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  20. Information transfer and recovery for the sense of touch.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rémi D Proville1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France. [4].ORCID 0000000258291344
Maria Spolidoro1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France. [4].
Nicolas Guyon1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France.ORCID 0000000312878606
Guillaume P Dugué1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France.
Fekrije Selimi1] Center for Interdisciplinary Research in Biology, Collège de France, Paris, France. [2] CNRS UMR7241, Paris, France. [3] INSERM U1050, Paris, France.
Philippe IsopeInstitut des Neurosciences Cellulaires et Intégratives, CNRS UPR 3212, Université de Strasbourg, Strasbourg, France.
Daniela Popa1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France. [4].
Clément Léna1] Institut de Biologie de l'Ecole Normale Supérieure, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS) UMR8197, Paris, France. [3] Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France. [4].
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensorimotor integration is crucial to perception and motor control. How and where this process takes place in the brain is still largely unknown. Here we analyze the cerebellar contribution to sensorimotor integration in the whisker system of mice. We identify an area in the cerebellum where cortical sensory and motor inputs converge at the cellular level. Optogenetic stimulation of this area affects thalamic and motor cortex activity, alters parameters of ongoing movements and thereby modifies qualitatively and quantitatively touch events against surrounding objects. These results shed light on the cerebellum as an active component of sensorimotor circuits and show the importance of sensorimotor cortico-cerebellar loops in the fine control of voluntary movements.

Indexed as

Afferent PathwaysAnimalsCerebellumEfferent PathwaysElectric StimulationMice, Inbred C57BLMice, TransgenicMovementOptogeneticsPonsPurkinje CellsSensorimotor CortexSpace PerceptionThalamusTouch PerceptionVibrissae

Identifiers

PMID25064850
OpenAlexW1984409525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.