ArticleEcotoxicology (London, England)2014
Ecotoxicity and environmental risk assessment of pharmaceuticals and personal care products in aquatic environments and wastewater treatment plants.
Article in Ecotoxicology (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Structural and Functional Changes in Biological Systems of Wastewater Treatment Plants Induced by Bicyclic Non-Steroidal Anti-Inflammatory Drugs-A Review.Molecules (Basel, Switzerland) · 2026Review
- Advanced strategies for the removal of venlafaxine from aqueous environments: a critical review of adsorption and advanced oxidation pathways.RSC advances · 2025Review
- Bacterial toxicity of Acetaminophen and Edaravone, and their binary mixtures: experimental and predicted values using traditional and novel Van Laar-based models.Ecotoxicology (London, England) · 2024Article
- Analytical Methods for the Determination of Pharmaceuticals and Personal Care Products in Solid and Liquid Environmental Matrices: A Review.Molecules (Basel, Switzerland) · 2024Review
- COVID-19 pandemic-related drugs and microplastics from mask fibers jointly affect soil functions and processes.Environmental science and pollution research international · 2024Article
- Can Pharmaceutical Excipients Threaten the Aquatic Environment? A Risk Assessment Based on the MicrotoxMolecules (Basel, Switzerland) · 2023Article
- An investigation on removal of ciprofloxacin and norfloxacin by phycoremediation with an emphasis on acute toxicity and biochemical composition.Scientific reports · 2023Article
- Molecular Dynamics Simulation Prediction of the Partitioning Constants (Environmental science & technology · 2023Article
- Phenotypic and metabolic adaptations ofFrontiers in microbiology · 2023Article
- Household Pharmaceutical Waste Disposal as a Global Problem-A Review.International journal of environmental research and public health · 2022Review
- Article
- Disposal of Unused and Expired Medicines within the Sunyani Municipality of Ghana: A Cross-Sectional Survey.Journal of environmental and public health · 2022Article
- A review on pharmaceuticals removal from waters by single and combined biological, membrane filtration and ultrasound systems.Ultrasonics sonochemistry · 2021Review
- Pharmaceuticals in source waters of 95 First Nations in Canada.Canadian journal of public health = Revue canadienne de sante publique · 2021Article
- Antibiotic resistance in the environment: a critical insight on its occurrence, fate, and eco-toxicity.Environmental science and pollution research international · 2021Review
- ZnO nanorods/FeEnvironmental science and pollution research international · 2021Article
- Article
- Photocatalytic degradation of diphenhydramine in aqueous solution by natural dolomite.RSC advances · 2020Article
- Adsorption, degradation, and mineralization of emerging pollutants (pharmaceuticals and agrochemicals) by nanostructures: a comprehensive review.Environmental science and pollution research international · 2020Review
- Toxic response of the bacterium Vibrio fischeri to sodium lauryl ether sulphate residues in excavated soils.Ecotoxicology (London, England) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A wide range of pharmaceuticals and personal care products (PPCPs) are present in the environment, and many of their adverse effects are unknown. The environmental risk assessment of 26 PPCPs of relevant consumption and occurrence in the aquatic environment in Spain was accomplished in this research. Based on the ecotoxicity values obtained by bioluminescence and respirometry assays and by predictions using the US EPA ecological structure-activity relationship (ECOSAR™), the compounds were classified following the Globally Harmonized System of Classification and Labelling of Chemicals. According to the criteria of the European Medicines Agency, the real risk of impact of these compounds in wastewater treatment plants (WWTPs) and in the aquatic environment was predicted. In at least two ecotoxicity tests, 65.4 % of the PPCPs under study showed high toxicity or were harmful to aquatic organisms. The global order of the species' sensitivity to the PPCPs considered was as follows: Vibrio fischeri (5 min) > Vibrio fischeri (15 min) > algae > crustaceans > fish > biomass of WWTP. Acetaminophen, ciprofloxacin, clarithromycin, clofibrate, ibuprofen, omeprazole, triclosan, parabens and 1,4-benzoquinone showed some type of risk for the aquatic environments and/or for the activated sludge of WWTPs. Development of acute and chronic ecotoxicity data, the determination of predicted and measured environmental concentrations of PPCPs, the inclusion of metabolites and transformation products and the evaluation of mixtures of these compounds will allow further improvements of the results of the ERAs and, finally, to efficiently identify the compounds that could affect the environment.
Indexed as
Identifiers
25064485What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.