Evidence map›Paper›PMID 25063838›Full record

ReviewExperimental physiology2014

Alterations in atrial perfusion during atrial fibrillation.

Christina F Pacchia, Derek J Dosdall, Ravi Ranjan, Edward DiBella

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Transient outward KAmerican journal of physiology. Heart and circulatory physiology · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christina F PacchiaComprehensive Arrhythmia and Research Management Center, Division of Cardiology, Department of Radiology, University of Utah Health Sciences Center, Salt Lake City, UT, USA christina.pacchia@hsc.utah.edu.
Derek J DosdallComprehensive Arrhythmia and Research Management Center, Division of Cardiology, Department of Radiology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
Ravi RanjanComprehensive Arrhythmia and Research Management Center, Division of Cardiology, Department of Radiology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
Edward DiBellaComprehensive Arrhythmia and Research Management Center, Division of Cardiology, Department of Radiology, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
University of Utah Health Care · USUniversity of Utah · US

Funding

Quantitative cardiac MRI perfusion for longitudinal studiesR01HL113224 · NHLBI · UNIVERSITY OF UTAH · PI DIBELLA, EDWARD VR · 2012 to 2015
$2.0M
NHLBI NIH HHS R01 HL113224
6 · The paper itself

Abstract

Left atrial (LA) perfusion during disease states has been a topic of much interest, because the clinical implications and detrimental effects of lack of blood flow to the atria are numerous. In the chronic setting, changes in perfusion may lead to LA ischaemia and structural remodelling, a factor implicated in the self-perpetuation of chronic atrial fibrillation (AF). The association between AF and altered LA perfusion has been studied, but a direct causal association between perfusion changes and AF has not been established. A comprehensive literature search of Medline, Embase and Google Scholar databases was conducted from 1960 to February 2014. We systematically analysed reference lists of physiological articles and reviews for other possibly relevant studies. The aim of this review is to provide a comprehensive discussion of the AF-mediated changes in LA perfusion and the potential mechanisms underlying the alterations in coronary flow to the LA in this setting. In addition, we discuss the clinical contexts in which changes in LA perfusion may be relevant. Finally, this article highlights the need for longitudinal studies of AF that would elucidate the changes in LA perfusion resulting from chronic AF and lead to advancements in effective treatments to prevent progression of this disease.

Indexed as

AnimalsAtrial FibrillationDisease ProgressionFibrosisHeart AtriaHumansMyocardial Ischemia

Identifiers

PMID25063838
PMCPMC4456009
OpenAlexW1585586129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.