ArticleGenome biology and evolution2014
Highly variable recombinational landscape modulates efficacy of natural selection in birds.
Article in Genome biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Opinion: Why Sex-Based Genomic Differentiation Should Not Be Overlooked in Population Genetics.Molecular ecology · 2025Article
- Diverse evolutionary trajectories of mitocoding DNA in mammalian and avian nuclear genomes.Genome research · 2025Article
- The CpG Landscape of Protein Coding DNA in Vertebrates.Evolutionary applications · 2025Article
- Understanding the Genetic Basis of Variation in Meiotic Recombination: Past, Present, and Future.Molecular biology and evolution · 2024Review
- Increased Positive Selection in Highly Recombining Genes Does not Necessarily Reflect an Evolutionary Advantage of Recombination.Molecular biology and evolution · 2024Article
- A region of suppressed recombination misleads neoavian phylogenomics.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The role of recombination dynamics in shaping signatures of direct and indirect selection across theProceedings. Biological sciences · 2024Article
- Extreme variation in recombination rate and genetic diversity along the Sylvioidea neo-sex chromosome.Molecular ecology · 2022Article
- Genetic variation along an altitudinal gradient in theFrontiers in microbiology · 2022Article
- From molecules to populations: appreciating and estimating recombination rate variation.Nature reviews. Genetics · 2020Review
- A Study of Faster-Z Evolution in the Great Tit (Parus major).Genome biology and evolution · 2020Article
- Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds.Genome biology and evolution · 2019Article
- The Old and the New: Discovery Proteomics Identifies Putative Novel Seminal Fluid Proteins in Drosophila.Molecular & cellular proteomics : MCP · 2019Article
- Biased Inference of Selection Due to GC-Biased Gene Conversion and the Rate of Protein Evolution in Flycatchers When Accounting for It.Molecular biology and evolution · 2018Article
- Human long intrinsically disordered protein regions are frequent targets of positive selection.Genome research · 2018Article
- Determinants of the Efficacy of Natural Selection on Coding and Noncoding Variability in Two Passerine Species.Genome biology and evolution · 2017Article
- Predictive Models of Recombination Rate Variation across the Drosophila melanogaster Genome.Genome biology and evolution · 2016Article
- Transcriptomes of Plant Gametophytes Have a Higher Proportion of Rapidly Evolving and Young Genes than Sporophytes.Molecular biology and evolution · 2016Article
- Recombination Rate Variation Modulates Gene Sequence Evolution Mainly via GC-Biased Gene Conversion, Not Hill-Robertson Interference, in an Avian System.Molecular biology and evolution · 2016Article
- The relationship of recombination rate, genome structure, and patterns of molecular evolution across angiosperms.BMC evolutionary biology · 2015Article
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5 authors.
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Abstract
Determining the rate of protein evolution and identifying the causes of its variation across the genome are powerful ways to understand forces that are important for genome evolution. By using a multitissue transcriptome data set from great tit (Parus major), we analyzed patterns of molecular evolution between two passerine birds, great tit and zebra finch (Taeniopygia guttata), using the chicken genome (Gallus gallus) as an outgroup. We investigated whether a special feature of avian genomes, the highly variable recombinational landscape, modulates the efficacy of natural selection through the effects of Hill-Robertson interference, which predicts that selection should be more effective in removing deleterious mutations and incorporating beneficial mutations in high-recombination regions than in low-recombination regions. In agreement with these predictions, genes located in low-recombination regions tend to have a high proportion of neutrally evolving sites and relaxed selective constraint on sites subject to purifying selection, whereas genes that show strong support for past episodes of positive selection appear disproportionally in high-recombination regions. There is also evidence that genes located in high-recombination regions tend to have higher gene expression specificity than those located in low-recombination regions. Furthermore, more compact genes (i.e., those with fewer/shorter introns or shorter proteins) evolve faster than less compact ones. In sum, our results demonstrate that transcriptome sequencing is a powerful method to answer fundamental questions about genome evolution in nonmodel organisms.
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