Evidence map›Paper›PMID 25062797›Full record

ArticleInternational journal of hematology2014

Successful treatment of histiocytic sarcoma with induction chemotherapy consisting of dose-escalated CHOP plus etoposide and upfront consolidation auto-transplantation.

Hideki Tsujimura, Toshiko Miyaki, Shuhei Yamada, Takeaki Sugawara, Mikiko Ise, Shintaro Iwata, Tsukasa Yonemoto, Dai Ikebe, Makiko Itami, Kyoya Kumagai

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Histiocytic Sarcoma: A Review and Update.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Somatic mutations in histiocytic sarcoma identified by next generation sequencing.Virchows Archiv : an international journal of pathology · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hideki TsujimuraDivision of Hematology-Oncology, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba, 260-8717, Japan, htsujimu@chiba-cc.jp.
Toshiko Miyaki
Shuhei Yamada
Takeaki Sugawara
Mikiko Ise
Shintaro Iwata
Tsukasa Yonemoto
Dai Ikebe
Makiko Itami
Kyoya Kumagai
Chiba Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histiocytic sarcoma (HS) is an extremely rare malignant neoplasm that often exhibits an aggressive clinical presentation. In this report, we describe the case of a 38-year-old female with advanced-stage HS who was found to have a subcutaneous tumor in the left calf and enlarged lymph nodes in the left inguinal and internal iliac regions. The subcutaneous tumor and inguinal nodes were resected operatively. Immunohistochemistry of the surgical specimens showed that the malignant cells stained positive for CD163, CD68, and related markers; a diagnosis of HS was established. Following the administration of induction chemotherapy consisting of dose-escalated CHOP plus etoposide, the remaining internal iliac tumors disappeared. At that point, high-dose chemotherapy with autologous stem cell transplantation was performed as consolidation treatment. The patient remains alive with no evidence of disease for 30 months post-treatment. This report provides valuable insight into the treatment of advanced HS.

Indexed as

Hematopoietic Stem Cell TransplantationAdultAntineoplastic Combined Chemotherapy ProtocolsBiopsyConsolidation ChemotherapyCyclophosphamideDoxorubicinEtoposideFemaleFluorodeoxyglucose F18Histiocytic SarcomaHumansInduction ChemotherapyMagnetic Resonance ImagingPositron-Emission TomographyPrednisoneCyclophosphamideDoxorubicinEtoposideFluorodeoxyglucose F18PrednisoneVincristine

Identifiers

PMID25062797
OpenAlexW2090382036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.