Evidence map›Paper›PMID 25061602›Full record

Trial reportBioMed research international2014

Involvement of the inconstant bursa of the fifth metatarsophalangeal joint in psoriatic arthritis: a clinical and ultrasonographic study.

Giovanni Ciancio, Stefania Volpinari, Maria Fotinidi, Federica Furini, Ilaria Farina, Alessandra Bortoluzzi, Manuela Ferracin, Francesca Bandinelli, Carlo Orzincolo, Francesco Trotta and 1 more

Open access · hybridAbstract readClinical TrialComparative Study
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Giovanni CiancioRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.
Stefania VolpinariRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.
Maria FotinidiRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.
Federica FuriniRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.
Ilaria FarinaRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.ORCID 0000-0002-2965-0088
Alessandra BortoluzziRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.ORCID 0000-0003-2416-8134
Manuela FerracinDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Via Fossato di Mortara 64/b, 44121 Ferrara, Italy.ORCID 0000-0002-1595-6887
Francesca BandinelliDepartment of Internal Medicine, Rheumatology Division, University of Florence, Viale Pieraccini 18, 50139 Florence, Italy.
Carlo OrzincoloDepartment of Radiology, AUSL of Ravenna, Viale Stradone 9, 48018 Ravenna, Italy.
Francesco TrottaRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.
Marcello GovoniRheumatology Unit, Department of Medical Sciences, University of Ferrara and S. Anna University Hospital, Via Aldo Moro 8, 44124 Cona, Ferrara, Italy.ORCID 0000-0003-0499-5773
University of Ferrara · ITOspedale "Santa Maria delle Croci" di Ravenna · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the involvement of the bursa located next to the head of the 5th metatarsal bone in patients with psoriatic arthritis (PsA) in comparison with the other seronegative spondyloarthritis (SpA).

methodsAll patients with PsA seen during a period of 24 months were enrolled. The control group included healthy subjects and patients with the other SpA. All subjects underwent clinical and ultrasound (US) examination of the lateral surface of the 5th metatarsal.

results150 PsA patients (88 M; 62 F), 172 SpA (107 M; 65 F), and 95 healthy controls (58 M; 37 F) were evaluated. Based on clinical and US evaluation, bursitis was diagnosed in 17/150 (11.3%) PsA patients but in none of the SpA (P < 0.0001) and healthy (P = 0.0002) controls. In detecting bursitis, US was more sensitive than clinical examination, although the difference did not reach statistical significance (P = 0.09).

conclusionThe bursa of the 5th metatarsophalangeal joint appears to be involved in PsA more frequently than by chance. If confirmed by other studies, this finding could be considered as a distinctive clinical sign of PsA, useful for differential diagnosis with the other SpA. In asymptomatic patients, US proved to be more sensitive in the detection of bursitis.

Indexed as

AdultAgedArthritis, PsoriaticBursa, SynovialBursitisDiagnosis, DifferentialHumansMaleMetatarsophalangeal JointSpondylitis, AnkylosingUltrasonography

Identifiers

PMID25061602
PMCPMC4100366
OpenAlexW1969386280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.