ArticleJournal of gastric cancer2014
Occult gastric cancer presenting as hypoxia from pulmonary tumor thrombotic microangiopathy.
Article in Journal of gastric cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Clinical Course of Suspected Diagnosis of Pulmonary Tumor Thrombotic Microangiopathy: A 10-Year Experience of Rapid Progressive Right Ventricular Failure Syndrome in Advanced Cancer Patients.Korean circulation journal · 2023Article
- Pulmonary tumor thrombotic microangiopathy of patient with both hepatocellular carcinoma and gastric signet-ring cell carcinoma: a case report and review of literature.Translational cancer research · 2021Article
- A slowly-growing solitary skip lymph nodule of occult gastric cancer above the neck of pancreas: a case report.Surgical case reports · 2020Article
- Gastric adenocarcinoma revealed by atypical pulmonary lymphangitic carcinomatosis.Journal of gastrointestinal oncology · 2018Article
- Pulmonary Tumor Thrombotic Microangiopathy: Case Report and Literature Review.Journal of acute medicine · 2018Article
- Subacute right heart failure revealing three simultaneous causes of post-embolic pulmonary hypertension in metastatic dissemination of breast cancer.ESC heart failure · 2017Article
- Ante-mortem diagnosis of pulmonary tumour thrombotic microangiopathy in a patient with unrecognised extramammary Paget's disease.BMJ case reports · 2016Article
- Fatal pulmonary tumor thrombotic microangiopathy caused by undiagnosed metastatic gastric adenocarcinoma.Proceedings (Baylor University. Medical Center) · 2015Article
- A case of pulmonary tumour thrombotic microangiopathy.Respiratory medicine case reports · 2015Article
- Pulmonary tumor thrombotic microangiopathy: a systematic review.Pulmonary circulationArticle
- Pulmonary Tumor Embolism and Pulmonary Tumor Thrombotic Microangiopathy Causing Rapidly Progressive Respiratory Failure: A Case Series.Journal of investigative medicine high impact case reportsArticle
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary tumor thrombotic microangiopathy (PTTM) causing fatal pulmonary hypertension is a rare presentation of malignancy. In general, patients with PTTM rapidly succumb to death due to severe hypoxia. To date, very few cases of PTTM have been reported in the literature; and most of these cases were from gastric cancer and were diagnosed on post mortem autopsy, as it is extremely challenging to make an ante mortem diagnosis. We here report on a case of undiagnosed diffuse gastric cancer, presenting as worsening hypoxia. The clinical, radiographic, and echocardiographic features, and laboratory and pathological results were consistent with PTTM from gastric cancer. The patient was started on anticoagulation therapy, corticosteroids, and high-flow oxygen. However, her hypoxia worsened to the extent that she required ventilator support, and she died soon after intubation due to cardiac arrest. Since diffuse gastric cancer is associated with hereditary diffuse gastric cancer syndrome, cadherin 1 gene mutation analysis was performed to estimate the risk to her daughters. The test came back negative.
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