ArticleSleep2014
Sleep promotes cortical response potentiation following visual experience.
Article in Sleep, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed, 129 citations in OpenAlex.
- Review
- Article
- Modulating sleep: slow oscillation and spindle stimulation effects on physiology and memory.NPJ science of learning · 2026Article
- Experience-Dependent Plasticity to Visual Sequences in Mouse Anterior Cingulate Cortex Reflects Familiarity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Temporary retinal inactivation reverses effects of long-term monocular deprivation in visual cortex by induction of burst mode firing in the thalamus.Cell reports · 2025Article
- Sleep and experience-dependent visual plasticity in the adult cerebral cortex: an update.Sleep · 2025Article
- Local thalamic interneurons drive spindle termination and enable sleep-dependent learning.bioRxiv : the preprint server for biology · 2025Article
- Brief sleep disruption following hippocampus-dependent learning downscales interneuron synapses within lateral entorhinal cortex.bioRxiv : the preprint server for biology · 2025Article
- Article
- Rapid prey capture learning drives a slow resetting of network activity in rodent binocular visual cortex.bioRxiv : the preprint server for biology · 2025Article
- Sleep-wake-related changes in intracellular chloride regulate plasticity at glutamatergic cortical synapses.Current biology : CB · 2025Article
- Sleep is necessary for experience-dependent sequence plasticity in mouse primary visual cortex.Sleep · 2025Article
- Article
- Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons.bioRxiv : the preprint server for biology · 2025Article
- REM refines and rescues memory representations: a new theory.Sleep advances : a journal of the Sleep Research Society · 2025Review
- Rapid and cumulative adult plasticity in the mouse visual cortex.Frontiers in neural circuits · 2025Article
- Stimulus-specific enhancement in mouse visual cortex requires GABA but not VIP-peptide release from VIP interneurons.Journal of neurophysiology · 2024Article
- Sleep deprivation drives brain-wide changes in cholinergic presynapse abundance inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Targeting the circadian modulation: novel therapeutic approaches in the management of ASD.Frontiers in psychiatry · 2024Review
- Repeated passive visual experience modulates spontaneous and non-familiar stimuli-evoked neural activity.Scientific reports · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
STUDY
objectivesSleep has been hypothesized to globally reduce synaptic strength. However, recent findings suggest that in the context of learning and memory consolidation, sleep may promote synaptic potentiation. We tested the requirement for sleep in a naturally occurring form of experience-dependent synaptic potentiation in the adult mouse visual cortex (V1), which is initiated by patterned visual experience.
designVisual responses were recorded in individual V1 neurons before and after presentation of an oriented grating stimulus, and after subsequent sleep or sleep deprivation. MEASUREMENTS AND
resultsWe find that V1 response potentiation-associated with a shift in orientation preference in favor of the presented stimulus-occurs only after sleep and only during the entrained circadian sleep phase, and is blocked by sleep deprivation. Induction of plasticity following stimulus presentation is associated with an increase in principal neuron firing in V1, which is present in all behavioral states and occurs regardless of time of day. Sleep dependent potentiation is proportional to phase-locking of neuronal activity with thalamocortical spindle oscillations.
conclusionsOur results suggest that sleep can promote cortical synaptic potentiation in vivo, and that this potentiation may be mediated by slow wave sleep spindles. CITATION: Aton SJ, Suresh A, Broussard C, Frank MG. Sleep promotes cortical response potentiation following visual experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.