Evidence map›Paper›PMID 25061135›Full record

ArticleDiabetes care2014

NIDDK international conference report on diabetes and depression: current understanding and future directions.

Richard I G Holt, Mary de Groot, Irwin Lucki, Christine M Hunter, Norman Sartorius, Sherita H Golden

Open access · greenAbstract read
In one paragraph

Article in Diabetes care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 151 citations in OpenAlex.

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  5. Trial
  6. Barriers to Self-Management in Depressed Women With Type 2 Diabetes.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2017
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Richard I G HoltHuman Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, U.K. r.i.g.holt@soton.ac.uk.
Mary de GrootDiabetes Translational Research Center, Indiana University School of Medicine, Indianapolis, IN.
Irwin LuckiDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Christine M HunterNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Norman SartoriusAssociation for the Improvement of Mental Health Programmes and the Dialogue on Diabetes and Depression, Geneva, Switzerland.
Sherita H GoldenDepartments of Medicine and Epidemiology, Johns Hopkins University Schools of Medicine and Public Health, Baltimore, MD.
Indiana University School of MedicineJohns Hopkins University · USNational Institutes of Health · USThe Geneva Association · CHUniversity of Pennsylvania · US

Funding

Program ACTIVE II: Behavioral Depression Treatment for Type 2 DiabetesR18DK092765 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI DE GROOT, MARY K. · 2011 to 2015
$3.2M
NIDDK NIH HHS R18 DK092765
6 · The paper itself

Abstract

Comorbid diabetes and depression are a major clinical challenge as the outcomes of each condition are worsened by the other. This article is based on the presentations and discussions during an international meeting on diabetes and depression convened by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in collaboration with the National Institute of Mental Health and the Dialogue on Diabetes and Depression. While the psychological burden of diabetes may contribute to depression in some cases, this explanation does not sufficiently explain the relationship between these two conditions. Shared biological and behavioral mechanisms, such as hypothalamic-pituitary-adrenal axis activation, inflammation, autonomic dysfunction, sleep disturbance, inactive lifestyle, poor dietary habits, and environmental and cultural risk factors, are important to consider in understanding the link between depression and diabetes. Both individual psychological and pharmacological depression treatments are effective in people with diabetes, but the current range of treatment options is limited and has shown mixed effects on glycemic outcomes. More research is needed to understand what factors contribute to individual differences in vulnerability, treatment response, and resilience to depression and metabolic disorders across the life course and how best to provide care for people with comorbid diabetes and depression in different health care settings. Training programs are needed to create a cross-disciplinary workforce that can work in different models of care for comorbid conditions.

Indexed as

Blood GlucoseCongresses as TopicDepressive DisorderDiabetes MellitusDiabetic NephropathiesForecastingHumansHypothalamo-Hypophyseal SystemInflammationPituitary-Adrenal SystemRisk FactorsSedentary BehaviorSleep Wake DisordersUnited StatesBlood Glucose

Identifiers

PMID25061135
PMCPMC4113168
OpenAlexW2000417204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.