Evidence map›Paper›PMID 25060054›Full record

ArticleJournal of the American Society of Nephrology : JASN2015

Cutting it out: ENaC processing in the human nephron.

Evan C Ray, Thomas R Kleyman

Abstract readEditorialComment
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Influence of proteolytic cleavage of ENaC's γ subunit upon NaAmerican journal of physiology. Renal physiology · 2024
    Article
  2. Article
  3. Trypsin-Like Proteases and Their Role in Muco-Obstructive Lung Diseases.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Epithelial NaAnnual review of physiology · 2018
    Review
  8. Protease-activated receptors in kidney disease progression.American journal of physiology. Renal physiology · 2016
    Review
  9. Article
  10. Renal sodium transport in renin-deficient Dahl salt-sensitive rats.Journal of the renin-angiotensin-aldosterone system : JRAAS · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Evan C RayDepartment of Medicine and.
Thomas R KleymanDepartment of Medicine and Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania kleyman@pitt.edu.

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACKSON, EDWIN KERRY · 2008 to 2022
$13.4M
Renal and Epithelial Biology Training ProgramT32DK061296 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2002 to 2022
$3.1M
Sodium Channel BiogenesisR01DK065161 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUGHEY, REBECCA P, KLEYMAN, THOMAS R · 2004 to 2013
$2.8M
NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK065161NIDDK NIH HHS R01DK065161NIDDK NIH HHS T32 DK061296
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epithelial Sodium ChannelsFemaleHumansKidneyMaleEpithelial Sodium ChannelsSCNN1G protein, humanENaCplasminprostasinprotease

Identifiers

PMID25060054
PMCPMC4279749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.