Evidence map›Paper›PMID 25059941›Full record

ReviewLancet (London, England)2015

HIV risk and preventive interventions in transgender women sex workers.

Tonia Poteat, Andrea L Wirtz, Anita Radix, Annick Borquez, Alfonso Silva-Santisteban, Madeline B Deutsch, Sharful Islam Khan, Sam Winter, Don Operario

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04962997 (Health Status of Transgender Women in French Guiana and Paris), which is not on this map. Cited by 205 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
205citing papers in PubMed, 11 pooled it
100.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04962997 completednot on this mapstarted 2021, after this paper: background citation

Health Status of Transgender Women in French Guiana and Paris: a Cross-sectional View (TransGuyane)

TypeobservationalSponsorCentre Hospitalier de CayenneRan2021 to 2023Enrolled46ConditionsSexual Health, Mental HealthArmsData collection
3 · Its place in the literature

Who cites it

205 citing papers in PubMed, 11 syntheses or guidelines pooled it, 361 citations in OpenAlex.

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  10. Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People.Journal of acquired immune deficiency syndromes (1999) · 2016
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145 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Tonia PoteatDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: tpoteat@jhsph.edu.
Andrea L WirtzJohns Hopkins Medical Institute, Baltimore, MD, USA.
Anita RadixCallen Lorde Community Health Center, New York, NY, USA.
Annick BorquezThe HIV Modelling Consortium, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Alfonso Silva-SantistebanUnit of Health, Sexuality and Human Development, Universidad Peruana Cayetano Heredia, Lima, Peru.
Madeline B DeutschCenter of Excellence for Transgender Health, Department of Family and Community Medicine, University of California-San Francisco, San Francisco, CA, USA.
Sharful Islam KhanThe Global Fund Project, Center for HIV and AIDS, icddr,b, Dhaka, Bangladesh.
Sam WinterDivision of Policy and Social Studies in Education, Faculty of Education, University of Hong Kong, Hong Kong, China.
Don OperarioSchool of Public Health, Brown University, Department of Behavioral and Social Sciences, Providence, RI, USA.
Bloomberg (United States) · USBrown University · USCommunity Health Center · USImperial College London · GBInternational Centre for Diarrhoeal Disease Research · BDUniversidad Peruana Cayetano Heredia · PEUniversity of California, San Francisco · USUniversity of Hong Kong · HK

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Bryan Lau · 2012 to 2026
$67.0M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
NIAID NIH HHS 1P30AI094189NIAID NIH HHS P30 AI094189NICHD NIH HHS R25 HD045810
6 · The paper itself

Abstract

Worldwide, transgender women who engage in sex work have a disproportionate risk for HIV compared with natal male and female sex workers. We reviewed recent epidemiological research on HIV in transgender women and show that transgender women sex workers (TSW) face unique structural, interpersonal, and individual vulnerabilities that contribute to risk for HIV. Only six studies of evidence-based prevention interventions were identified, none of which focused exclusively on TSW. We developed a deterministic model based on findings related to HIV risks and interventions. The model examines HIV prevention approaches in TSW in two settings (Lima, Peru and San Francisco, CA, USA) to identify which interventions would probably achieve the UN goal of 50% reduction in HIV incidence in 10 years. A combination of interventions that achieves small changes in behaviour and low coverage of biomedical interventions was promising in both settings, suggesting that the expansion of prevention services in TSW would be highly effective. However, this expansion needs appropriate sustainable interventions to tackle the upstream drivers of HIV risk and successfully reach this population. Case studies of six countries show context-specific issues that should inform development and implementation of key interventions across heterogeneous settings. We summarise the evidence and knowledge gaps that affect the HIV epidemic in TSW, and propose a research agenda to improve HIV services and policies for this population.

Indexed as

CondomsFemaleHealth Services AccessibilityHIV InfectionsHumansMalePeruPrejudiceRisk FactorsSan FranciscoSex WorkersSocial StigmaSocial SupportTransgender Persons

Identifiers

PMID25059941
PMCPMC4320978
OpenAlexW2138910933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.