ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2015
Development and validation of a disease-targeted quality of life instrument for chronic diverticular disease: the DV-QOL.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis (PROF). The "PROF" Study.
Comparing Placebo Versus Antibiotics for Acute Uncomplicated Diverticulitis
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Complicated Intraabdominal Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Pooled it
- Patient-Reported Outcome Measures in Colon and Rectal Surgery: A Systematic Review and Quality Assessment.Diseases of the colon and rectum · 2020Pooled it
- A systematic review of dimensions evaluating patient experience in chronic illness.Health and quality of life outcomes · 2019Pooled it
- A Novel Decision Aid for Colectomy in Diverticulitis: Cluster Randomized Pilot and Feasibility Study.Diseases of the colon and rectum · 2025Trial
- Impact of elective minimally invasive sigmoidectomy for diverticular disease on quality of life: a single-center study.Updates in surgery · 2026Article
- Article
- Observational
- Success in Diverticulitis Management: What Outcomes Really Matter?Clinics in colon and rectal surgery · 2025Review
- The DIVIPACT cohort profile: Evaluating the impact of colonic diverticulosis on daily life.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Reoperation and mortality following elective surgery for chronic and recurrent colonic diverticular disease: A nationwide population-based cohort study.International journal of colorectal disease · 2025Article
- Quality of life in diverticular disease: translation and validation of the Danish version of the diverticulitis quality of life instrument (DV‑QOL).International journal of colorectal disease · 2025Article
- Dietary and lifestyle insulinemic potentials, plasma metabolome, and risk of diverticulitis: a prospective cohort study.The American journal of clinical nutrition · 2024Article
- Quality of life with diverticular disease: translation and validation of the German version of the diverticulitis quality of life questionnaire (DV-QOL).Techniques in coloproctology · 2024Article
- Site and duration of abdominal pain discriminate symptomatic uncomplicated diverticular disease from previous diverticulitis patients.Internal and emergency medicine · 2024Observational
- The Patient Perspective on Colectomy for Recurrent Diverticulitis: A Qualitative Study.Annals of surgery · 2024Article
- Patient-Reported Outcomes in Colorectal Surgery.Clinics in colon and rectal surgery · 2023Review
- Diverticulitis is a population health problem: Lessons and gaps in strategies to implement and improve contemporary care.World journal of gastrointestinal surgery · 2023Review
- Symptomatic Uncomplicated Diverticular Disease (SUDD): Practical Guidance and Challenges for Clinical Management.Clinical and experimental gastroenterology · 2023Review
- What's in a Number? Assessing the Burden of Diverticular Disease.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Collection and Utilization of Patient-Reported Outcome Measures in a Colorectal Surgery Clinic.The Journal of surgical research · 2022Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColonic diverticular disease is typically conceived as acute diverticulitis attacks surrounded by periods of clinical silence. However, evolving data indicate that many patients have persistent symptoms and diminished health-related quality of life (HRQOL) long after acute attacks. We developed a disease-targeted HRQOL measure for symptomatic uncomplicated diverticular disease (SUDD)-the diverticulitis quality of life (DV-QOL) instrument.
methodsWe conducted a systematic literature review to craft a conceptual model of SUDD HRQOL. This was complemented by three focus groups including 45 SUDD patients. We developed items based on our literature search, focus groups, and cognitive debriefings. We administered the items to SUDD patients with persistent symptoms following a confirmed diverticulitis event. We created scales based on factor analysis and evaluated the scales for reliability and validity.
resultsConcept elicitation revealed a range of illness experiences attributed to SUDD. Coding of 20,490 transcribed words yielded a 52-code network with four primary, condition-related concepts: (1) physical symptoms (e.g., bloating); (2) behaviors (e.g., restrictions); (3) cognitions and concerns (e.g., fear); and (4) impact and consequences (e.g., absenteeism, anxiety). Based on patient language, we developed the 17-item DV-QOL instrument. In a cross-sectional validation sample of 197 patients, DV-QOL discriminated between patients with recent versus distant diverticulitis events and correlated highly with Short Form 36 and hospital anxiety and depression scores.
conclusionsPatients with SUDD attribute a wide range of negative psychological, social, and physical symptoms to their condition, both during and after acute attacks; DV-QOL captures these symptoms in a valid, reliable manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.