Evidence map›Paper›PMID 25059108›Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2014

Metabolically healthy and unhealthy obese--the 2013 Stock Conference report.

D Samocha-Bonet, V D Dixit, C R Kahn, R L Leibel, X Lin, M Nieuwdorp, K H Pietiläinen, R Rabasa-Lhoret, M Roden, P E Scherer and 2 more

Abstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 161 citations in OpenAlex.

  1. Trial
  2. Short-Term Estrogen Withdrawal Increases Adiposity in Healthy Men.The Journal of clinical endocrinology and metabolism · 2016
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  15. Tirzepatide-Induced Ketoacidosis in Non-Diabetic Patients.European journal of case reports in internal medicine · 2024
    Article
  16. Article
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  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 8 countries.

D Samocha-BonetGarvan Institute of Medical Research, University of New South Wales, Sydney, NSW, Australia.
V D Dixit
C R Kahn
R L Leibel
X Lin
M Nieuwdorp
K H Pietiläinen
R Rabasa-Lhoret
M Roden
P E Scherer
S Klein
E Ravussin
Chinese Academy of Sciences · CNColumbia University · USDeutsches Diabetes-Zentrum e.V. · DEGarvan Institute of Medical Research · AUJoslin Diabetes Center · USPennington Biomedical Research Center · USThe University of Texas Southwestern Medical Center · USUniversité de Montréal · CAUniversity of Amsterdam · NLUniversity of Helsinki · FIWashington University in St. Louis · USYale University · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI JEAN E. SCHAFFER · 1986 to 2026
$50.5M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
Developmental genes, miRNAs and adipose tissueR01DK082659 · NIDDK · JOSLIN DIABETES CENTER · PI C RONALD KAHN · 2009 to 2026
$10.7M
Insulin Receptor Substrates and Insulin ActionR01DK033201 · NIDDK · JOSLIN DIABETES CENTER · PI KAHN, C RONALD · 1986 to 2016
$10.6M
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK082659
6 · The paper itself

Abstract

Obesity is closely associated with cardiovascular diseases and type 2 diabetes, but some obese individuals, despite having excessive body fat, exhibit metabolic health that is comparable with that of lean individuals. The 'healthy obese' phenotype was described in the 1980s, but major advancements in its characterization were only made in the past five years. During this time, several new mechanisms that may be involved in health preservation in obesity were proposed through the use of transgenic animal models, use of sophisticated imaging techniques and in vivo measurements of insulin sensitivity. However, the main obstacle in advancing our understanding of the metabolically healthy obese phenotype and its related long-term health risks is the lack of a standardized definition. Here, we summarize the proceedings of the 13th Stock Conference of the International Association of the Study of Obesity. We describe the current research and highlight the unanswered questions and gaps in the field. Better understanding of metabolic health in obesity will assist in therapeutic decision-making and help identify therapeutic targets to improve metabolic health in obesity.

Indexed as

Insulin ResistancePhenotypeBlood GlucoseBody Mass IndexCardiovascular DiseasesCongresses as TopicDecision Support Systems, ClinicalGene-Environment InteractionHumansMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseObesityReference StandardsRisk FactorsBlood GlucoseInsulin sensitivemetabolically healthymetabolic syndromeobesity

Identifiers

PMID25059108
PMCPMC4519075
OpenAlexW1935184657

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.