Evidence map›Paper›PMID 25058221›Full record

ArticleJAMA2014

The intention-to-treat principle: how to assess the true effect of choosing a medical treatment.

Michelle A Detry, Roger J Lewis

2 registry-linked trialsAbstract readComment
PubMed Publisher
In one paragraph

Article in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 102 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02675569 naunknown statusnot on this mapstarted 2016, after this paper: background citation

ACCESS HD Pilot: A Randomized Trial Comparing Catheters to Fistulas in Elderly patientS Starting HemoDialysis

TypeinterventionalSponsorUniversity of CalgaryRan2016 to 2025Enrolled100ConditionsEnd-stage Kidney FailureArmsCatheter, Fistula
NCT05555472 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effectiveness of the Youth Initiated Mentoring Approach for Juvenile Delinquents

TypeinterventionalSponsorUniversity of AmsterdamRan2022 to 2024Enrolled300ConditionsJuvenile Delinquency, Youth Initiated Mentoring (YIM) ApproachArmsHalt-intervention, Youth Initiated Mentoring (YIM) approach
3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  5. Short-Term Outcomes of Single-Incision Versus Conventional Laparoscopic Surgery for Colorectal Diseases: Meta-Analysis of Randomized and Prospective Evidence.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Pooled it
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  10. Cognitive Orientation to Daily Occupational Performance (CO-OP) in Parkinson's: Randomized Trial Findings.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2026
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  14. A multicentre, prospective, randomized, open-label pragmatic trial to compare the effectiveness and safety of interferon beta-1a and glatiramer-acetate in paediatric patients affected by Multiple Sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michelle A DetryBerry Consultants LLC, Austin, Texas.
Roger J LewisBerry Consultants LLC, Austin, Texas2Department of Emergency Medicine, Harbor-UCLA Medical Center; Los Angeles Biomedical Research Institute; and David Geffen School of Medicine at UCLA, Torrance, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnemiaBrain InjuriesErythrocyte TransfusionErythropoietinFemaleHemoglobinsHumansMaleErythropoietinHemoglobins

Identifiers

PMID25058221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.