ReviewRadiology2014
CT perfusion of the liver: principles and applications in oncology.
Review in Radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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Who cites it
81 citing papers in PubMed.
- Clinical evaluation of in silico planning and real-time simulation of hepatic radiofrequency ablation (ClinicIMPPACT Trial).European radiology · 2020Trial
- Large-scale AI-guided liver malignancy diagnosis: multicenter study and a single-arm trial.Nature medicine · 2026Article
- A comparison of contrast-to-noise ratio of liver tumors between dynamic contrast-enhanced CT and respiration-tracked 4D-CT for radiotherapy targeting.The British journal of radiology · 2026Article
- Application value of gastric contrast ultrasonography in gastric tumors.Insights into imaging · 2026Review
- Model based noise correction enhances the accuracy of pancreatic CT perfusion blood flow measurements.Scientific reports · 2025Article
- Short-term repeatability and postprandial effect assessment of liver perfusion quantification in healthy subjects using arterial spin labeling MRI.Insights into imaging · 2025Article
- Contrast-enhanced CT as a non-invasive alternative for lung shunt fraction estimation in hepatic transarterial radioembolization.Radiology advances · 2025Article
- Evaluating the role of quantitative computed tomography perfusion parameters in differentiating hepatocellular carcinoma from other hepatic neoplasms.Abdominal radiology (New York) · 2025Article
- Non-contrast free-breathing liver perfusion imaging using velocity selective ASL combined with prospective motion compensation.Zeitschrift fur medizinische Physik · 2025Article
- Role of Artificial Intelligence in Nanomedicine and Organ-specific Therapy: An Updated Review.Current drug targets · 2025Review
- Pilot study of an arterial enhancement fraction-based model for progression prediction in HCC undergoing chemoembolization.Frontiers in oncology · 2025Article
- Performance evaluation of a 4D similarity filter for dynamic CT angiography imaging of the liver.Medical physics · 2024Article
- Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques.Journal of gastrointestinal cancer · 2024Review
- Translating contrast enhanced computed tomography images to liver radioembolization dose distribution for more comprehensively indicating patients.Physics in medicine and biology · 2024Article
- Usefulness of intratumoral perfusion analysis for assessing biological features of non-functional pancreatic neuroendocrine neoplasm.Langenbeck's archives of surgery · 2024Article
- Portal Venous and Hepatic Arterial Coefficients Predict Post-Hepatectomy Overall and Recurrence-Free Survival in Patients with Hepatocellular Carcinoma: A Retrospective Study.Journal of hepatocellular carcinoma · 2024Article
- Can spectral computed tomography (CT) replace perfusion CT to assess the histological classification of non-small cell lung cancer?Quantitative imaging in medicine and surgery · 2023Article
- Perfusion parameters of triphasic computed tomography hold preoperative prediction value for microvascular invasion in hepatocellular carcinoma.Scientific reports · 2023Article
- Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model.Insights into imaging · 2023Article
- Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
With the introduction of molecularly targeted chemotherapeutics, there is an increasing need for defining new response criteria for therapeutic success because use of morphologic imaging alone may not fully assess tumor response. Computed tomographic (CT) perfusion imaging of the liver provides functional information about the microcirculation of normal parenchyma and focal liver lesions and is a promising technique for assessing the efficacy of various anticancer treatments. CT perfusion also shows promising results for diagnosing primary or metastatic tumors, for predicting early response to anticancer treatments, and for monitoring tumor recurrence after therapy. Many of the limitations of early CT perfusion studies performed in the liver, such as limited coverage, motion artifacts, and high radiation dose of CT, are being addressed by recent technical advances. These include a wide area detector with or without volumetric spiral or shuttle modes, motion correction algorithms, and new CT reconstruction technologies such as iterative algorithms. Although several issues related to perfusion imaging-such as paucity of large multicenter trials, limited accessibility of perfusion software, and lack of standardization in methods-remain unsolved, CT perfusion has now reached technical maturity, allowing for its use in assessing tumor vascularity in larger-scale prospective clinical trials. In this review, basic principles, current acquisition protocols, and pharmacokinetic models used for CT perfusion imaging of the liver are described. Various oncologic applications of CT perfusion of the liver are discussed and current challenges, as well as possible solutions, for CT perfusion are presented.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.