Evidence map›Paper›PMID 25058087›Full record

ArticleJAMA2014

Topical and systemic antimicrobial therapy for venous leg ulcers.

Susan O'Meara, Rachel Richardson, Benjamin A Lipsky

Abstract readComment
PubMed Publisher
In one paragraph

Article in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Susan O'MearaSchool of Healthcare, Baines Wing, University of Leeds, England.
Rachel RichardsonCochrane Wounds Group, Department of Health Sciences, University of York, York, England.
Benjamin A LipskyDepartment of Medicine, University of Washington, Seattle4Department of Infectious Diseases, University of Geneva, Geneva, Switzerland5Green Templeton College, University of Oxford, Oxford, England.
University of Geneva · CHUniversity of Leeds · GBUniversity of York · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

clinical questionIs treatment with topical or systemic antimicrobial agents associated with better venous leg ulcer healing compared with usual care (dressings and bandages without antimicrobials) or an alternative topical or systemic antimicrobial agent? BOTTOM LINE: Available evidence, from underpowered pooled data, neither supports nor refutes an association of systemic antibiotic therapy with improved venous leg ulcer healing. Among topical antimicrobials, cadexomer iodine may be associated with better healing compared with usual care.

Indexed as

Anti-Bacterial AgentsAnti-Infective Agents, LocalHumansVaricose UlcerAnti-Bacterial AgentsAnti-Infective Agents, Local

Identifiers

PMID25058087
OpenAlexW2081614819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.