SynthesisPloS one2014
Pooled analysis of non-union, re-operation, infection, and approach related complications after anterior odontoid screw fixation.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The impact of odontoid screw fixation techniques on screw-related complications and fusion rates: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Pooled it
- Matched case-control study of odontoid osteosynthesis vs hard collar immobilisation for Type II odontoid fractures in the elderly: higher risk of adverse events with no long-term functional benefits.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Anterior Odontoid Screw Fixation: Current Advances in Indications and Techniques.Advances and technical standards in neurosurgery · 2026Review
- MFI-11 Predicts Post-Operative Serious Complications in Patients Undergoing Surgery for Odontoid Fractures.Global spine journal · 2025Article
- Two-screw osteosynthesis is biomechanically superior to single-screw osteosynthesis for type II odontoid fractures.Scientific reports · 2024Article
- Using Frailty Measures to Predict Functional Outcomes and Mortality After Type II Odontoid Fracture in Elderly Patients: A Retrospective Cohort Study.Global spine journal · 2024Article
- Article
- Odontoid Type II fractures in elderly: what are the real management goals and how to best achieve them? A multicenter European study on functional outcome.Neurosurgical review · 2022Article
- Modified anterior transarticular C1/2 fixation for odontoid fractures: An approach with high complication rate in geriatric population.Surgical neurology international · 2022Article
- Determination and optimization of ideal patient candidacy for anterior odontoid screw fixation.Surgical neurology international · 2021Article
- The Anterior Transarticular Fixation of C1/C2 in the Elderly With Dens Fractures.International journal of spine surgery · 2020Article
- Progress of the Anterior Transpedicular Screw in Lower Cervical Spine: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2019Review
- Development and Application of a No-Clog Surgical Suction Tip Using 3D Printing Technology.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Article
- Biomechanical Assessment of Stabilization of Simulated Type II Odontoid Fracture with Case Study.Asian spine journal · 2017Article
- Passage of an Anterior Odontoid Screw through Gastrointestinal Tract.Case reports in medicine · 2017Article
- Anterior transarticular atlantoaxial screw fixation in combination with dens screw fixation for type II odontoid fractures with associated atlanto-odontoid osteoarthritis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
- Anterior single odontoid screw placement for type II odontoid fractures: our modified surgical technique and initial results in a cohort study of 15 patients.F1000Research · 2016Article
- Conservative Management of Odontoid Peg Fractures, long term follow up.Journal of clinical orthopaedics and traumaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnterior odontoid screw fixation (AOSF) has been one of the most popular treatments for odontoid fractures. However, the true efficacy of AOSF remains unclear. In this study, we aimed to provide the pooled rates of non-union, reoperation, infection, and approach related complications after AOSF for odontoid fractures.
methodsWe searched studies that discussed complications after AOSF for type II or type III odontoid fractures. A proportion meta-analysis was done and potential sources of heterogeneity were explored by meta-regression analysis.
resultsOf 972 references initially identified, 63 were eligible for inclusion. 54 studies provided data regarding non-union. The pooled non-union rate was 10% (95% CI: 7%-3%). 48 citations provided re-operation information with a pooled proportion of 5% (95% CI: 3%-7%). Infection was described in 20 studies with an overall rate of 0.2% (95% CI: 0%-1.2%). The main approach related complication is postoperative dysphagia with a pooled rate of 10% (95% CI: 4%-17%). Proportions for the other approach related complications such as postoperative hoarseness (1.2%, 95% CI: 0%-3.7%), esophageal/retropharyngeal injury (0%, 95% CI: 0%-1.1%), wound hematomas (0.2%, 95% CI: 0%-1.8%), and spinal cord injury (0%, 95% CI: 0%-0.2%) were very low. Significant heterogeneities were detected when we combined the rates of non-union, re-operation, and dysphagia. Multivariate meta-regression analysis showed that old age was significantly predictive of non-union. Subgroup comparisons showed significant higher non-union rates in age ≥ 70 than that in age ≤ 40 and in age 40 to <50. Meta-regression analysis did not reveal any examined variables influencing the re-operation rate. Meta-regression analysis showed age had a significant effect on the dysphagia rate. CONCLUSIONS/SIGNIFICANCES: This study summarized the rates of non-union, reoperation, infection, and approach related complications after AOSF for odontoid fractures. Elderly patients were more likely to experience non-union and dysphagia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.