SynthesisPloS one2014
The prevalence of primary angle closure glaucoma in adult Asians: a systematic review and meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 5 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Non-contact tests for identifying people at risk of primary angle closure glaucoma.The Cochrane database of systematic reviews · 2020Pooled it
- Prevalence of Primary Angle Closure Glaucoma in the Last 20 Years: A Meta-Analysis and Systematic Review.Frontiers in medicine · 2020Pooled it
- National and subnational prevalence and burden of glaucoma in China: A systematic analysis.Journal of global health · 2017Pooled it
- Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.Nature genetics · 2016Pooled it
- Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma.PloS one · 2016Pooled it
- Trial
- Experimental Assessment of Iris Water Content and Sex Differences in Mature Rabbits.bioRxiv : the preprint server for biology · 2026Article
- Short-term outcomes of selective laser trabeculoplasty in pseudophakic primary angle-closure glaucoma after iridotomy: a retrospective pilot comparison with primary open-angle glaucoma.BMC ophthalmology · 2026Article
- Alterations in Retinal Vasculometry After Acute Primary Angle Closure Episode: A Comparative Analysis.Translational vision science & technology · 2026Article
- Investigation of laser peripheral iridotomy characteristics using the ImageJ program on anterior segment parameters.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Anterior Chamber Depth and the Long-Term Safety of Implantable Collamer Lens Surgery: A Case for Re-Evaluating Age-Stratified Indication Criteria.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Visco-circumferential-suture-trabeculotomy-synechiolysis with phacoemulsification versus phacoemulsification alone for chronic primary angle closure glaucoma.BMC ophthalmology · 2025Article
- Intelligent screening of narrow anterior chamber angle based on portable slit lamp.NPJ digital medicine · 2025Article
- Latin American Prevalence of Glaucoma: A Systematic Review and Meta-Analysis.Vision (Basel, Switzerland) · 2025Review
- Differences in the amplitude of dynamic low-frequency fluctuations in primary angle-closure glaucoma are associated with gene-molecular multi-omics.Frontiers in medicine · 2025Article
- Macular vascular density changes in different stages of chronic primary angle-closure glaucoma.Frontiers in medicine · 2025Article
- Undiagnosed glaucoma and its risk factors in the Yinzhou community-based glaucoma screening program.Frontiers in public health · 2025Article
- Assessment of factors affecting anterior chamber depth from data obtained from health checkup participants in Japan.Scientific reports · 2024Article
- Analysis of anterior segment in primary angle closure suspect with deep learning models.BMC medical informatics and decision making · 2024Article
- Glaucoma burden and its profile in a tertiary care centre of North-East India: A retrospective hospital-based study.Journal of family medicine and primary care · 2024Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary angle closure glaucoma (PACG) is higher in Asians than Europeans and Africans, with over 80% of PACG worldwide in Asia. Previous estimates of PACG were based largely on early studies, mostly using inappropriate case definitions. Therefore, we did a systematic review and meta-analysis to estimate the prevalence of PACG in adult Asian populations and to quantify its association with age, gender, and region.
methodsAll primary reports of population-based studies that reported the prevalence of PACG in adult Asian populations were identified. PACG case definition was compatible with the ISGEO definition. Twenty-nine population-based studies were included. The overall pooled prevalence estimates were calculated using a random effect model, and ethnicity-, age- and gender-specific pooled prevalence estimates were also calculated.
resultsThe overall pooled prevalence of PACG in those of adult Asians was 0.75% (95% CI, 0.58, 0.96). Ethnicity-specific pooled prevalence estimates were 0.97% (0.22, 4.27) in Middle East group, 0.66% (0.23, 1.86) in South East Asia group, 0.46% (0.32, 0.64) in India group, 1.10% (0.85, 1.44) in China group, and 1.19% (0.35, 3.98) in Japan group, respectively. Age-specific prevalence was 0.21% (0.12, 0.37) for those 40-49 years, 0.54% (0.34, 0.85) for those 50-59 years, 1.26% (0.93, 1.71) for those 60-69 years, and 2.32% (1.74, 3.08) for those 70 years or above. The overall female to male ratio of the PACG prevalence was 1.51∶1 (95% CI 1.01, 2.28).
conclusionsPACG affects approximately 0.75% adult Asians, increasing double per decade, and 60% of cases being female. The prevalence rates vary greatly by ethnic region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.