Evidence map›Paper›PMID 25057310›Full record

ArticleJournal of Cancer2014

Transcatheter arterial chemoembolization for intermediate-stage hepatocellular carcinoma: clinical outcome and safety in elderly patients.

Hiroki Nishikawa, Ryuichi Kita, Toru Kimura, Yoshiaki Ohara, Haruhiko Takeda, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado and 1 more

Abstract read
In one paragraph

Article in Journal of Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Outcome and Prognosis of Invasive Treatment for Hepatocellular Carcinoma in Very Elderly Patients Over 90 Years Old.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  5. Article
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  7. Article
  8. Article
  9. Aging of Liver in Its Different Diseases.International journal of molecular sciences · 2022
    Review
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  11. Article
  12. Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiroki NishikawaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Ryuichi KitaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Toru KimuraDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Yoshiaki OharaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Haruhiko TakedaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Azusa SakamotoDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Sumio SaitoDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Norihiro NishijimaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Akihiro NasuDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Hideyuki KomekadoDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.
Yukio OsakiDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of our study was to compare clinical outcomes between elderly patients aged ≥75 years (elderly group, n=66) with intermediate hepatocellular carcinoma (HCC) undergoing transcatheter arterial chemoembolization (TACE) and younger patients aged <75 years (control group, n=84) with intermediate HCC undergoing TACE.

methodsClinical outcomes, including overall survival (OS) and tumor response rate at initial therapy, were compared between these two groups.

resultsThe median survival time and the 1- and 3-year cumulative OS rates were 2.90 years and 84.1% and 48.0%, respectively, in the elderly group and 2.44 years and 78.2% and 39.3%, respectively, in the control group (p=0.887). The objective response rate in the elderly group was 81.8% (54/66 patients), while that in the control group was 78.6% (66/84 patients) (p=0.227).

conclusionElderly patients with intermediate HCC undergoing TACE had a prognosis comparable with that of younger patients with intermediate HCC undergoing TACE.

Indexed as

intermediate hepatocellular carcinomatranscatheter arterial chemoembolization

Identifiers

PMID25057310
PMCPMC4107235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.