Evidence map›Paper›PMID 25057231›Full record

ArticleThe Saudi dental journal2014

Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment.

Al-Dany A Atwa, Ramadan Y AbuShahba, Marwa Mostafa, Mohamed I Hashem

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Saudi dental journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02678104 (The Influence of Intra-alveolar Application of Honey on Healing Following Molar Teeth Extraction), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02678104 phase2unknown statusnot on this mapstarted 2016, after this paper: background citation

The Influence of Intra-alveolar Application of Honey on Healing Following Molar Teeth Extraction: A Randomized Clinical Trial

TypeinterventionalSponsorRiyadh Colleges of Dentistry and PharmacyRan2016 to 2017Enrolled100ConditionsDry SocketArmsTooth extraction, Chlorhexidine mouth wash, Intra-alveolar application of Manuka Honey
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Trial
  5. Trial
  6. Review
  7. Article
  8. Review
  9. Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Novel Insights into the Health Importance of Natural Honey.The Malaysian journal of medical sciences : MJMS · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Al-Dany A AtwaOrthodontic Department, Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt.
Ramadan Y AbuShahbaOrthodontic Department, Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt.
Marwa MostafaThe Regional Center for Myology and Biotechnology, Culture and Sensitivity Unit, Al-Azhar University, Cairo, Egypt.
Mohamed I HashemDental Health Department, College of Applied Medical Science, King Saud University, Saudi Arabia ; Dental Biomaterial Department, Al-Azhar University, Cairo, Egypt.
Al-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTHIS STUDY WAS CONDUCTED TO INVESTIGATE THE FOLLOWING: (1) the effects of chewing honey on plaque formation in orthodontic patients, (2) the effect of chewing honey on dental plaque bacterial counts, (3) determine if honey possesses antibacterial effects on bacteria recovered from plaques.

methodsFemale orthodontic patients (n = 20, 12-18 years of age) participated in this randomized controlled study. The effects of honey were compared to treatment with either 10% sucrose or 10% sorbitol that served as positive and negative controls, respectively. The pH of plaque was measured using a digital pH meter prior to baseline and at 2, 5, 10, 20, and 30 min after chewing honey or rinsing with control solutions and the numbers of Streptococcus mutans, Lactobacilli, and Prophymonas gingivalis in respective plaques were determined. The antibacterial activity of honey was tested against commonly used antibiotics using the disk diffusion method.

resultsSignificant differences in pH were observed in the honey and sucrose groups compared to the pH observed in the sorbitol group (p ⩽ 0.001). The maximum pH drop occurred at 5 min in both the honey and sucrose groups; however the pH in the honey group rapidly recovered 10-20 min after exposure and did not drop below the critical decalcification pH of 5.5. On the other hand, the pH following sucrose exposure fell <5.5 and was associated with a 30 min recovery time. The pH observed for the sorbitol group did not change over time. Bacterial counts were significantly reduced in the honey group compared to the other treatment groups (p ⩽ 0.001) and honey significantly inhibited the growth of all studied strains compared to inhibition observed with antibiotics (p ⩽ 0.001).

conclusionsHoney can be used as an alternative to traditional remedies for the prevention of dental caries and gingivitis following orthodontic treatment.

Indexed as

Bacterial countingHoneyOrthodontic treatmentpH measurementPlaque control

Identifiers

PMID25057231
PMCPMC4095052
OpenAlexW2096569475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.