Evidence map›Paper›PMID 25056977›Full record

ArticleBMJ open2014

Mapping patient pathways and estimating resource use for point of care versus standard testing and treatment of chlamydia and gonorrhoea in genitourinary medicine clinics in the UK.

Elisabeth J Adams, Alice Ehrlich, Katherine M E Turner, Kunj Shah, John Macleod, Simon Goldenberg, Robin K Meray, Vikki Pearce, Patrick Horner

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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  13. Point-by-Point Progress: Gonorrhea Point of Care Tests.Expert review of molecular diagnostics · 2020
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  15. Diagnostic accuracy of a prototype rapid chlamydia and gonorrhoea recombinase polymerase amplification assay: a multicentre cross-sectional preclinical evaluation.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Elisabeth J AdamsAquarius Population Health Limited, Bristol, UK School of Social and Community Medicine, University of Bristol, Bristol, UK.
Alice EhrlichAquarius Population Health Limited, Bristol, UK.
Katherine M E TurnerSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Kunj ShahAquarius Population Health Limited, Bristol, UK.
John MacleodSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Simon GoldenbergCentre for Clinical Infection & Diagnostics Research, Guy's & St Thomas' NHS Foundation Trust and King's College, London, UK.
Robin K MerayAquarius Population Health Limited, Bristol, UK.
Vikki PearceV Pearce Consulting Ltd, Hove, UK.
Patrick HornerSchool of Social and Community Medicine, University of Bristol, Bristol, UK Department of Genitourinary Medicine, NHS Bristol, Bristol, UK.
Aquarius Population Health · GBUniversity of Bristol · GBGuy's and St Thomas' NHS Foundation Trust · GBNorth Bristol NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to explore patient pathways using a chlamydia/gonorrhoea point-of-care (POC) nucleic acid amplification test (NAAT), and estimate and compare the costs of the proposed POC pathways with the current pathways using standard laboratory-based NAAT testing. DESIGN/

participantsWorkshops were conducted with healthcare professionals at four sexual health clinics representing diverse models of care in the UK. They mapped out current pathways that used chlamydia/gonorrhoea tests, and constructed new pathways using a POC NAAT. Healthcare professionals' time was assessed in each pathway. OUTCOME MEASURE: The proposed POC pathways were then priced using a model built in Microsoft Excel, and compared to previously published costs for pathways using standard NAAT-based testing in an off-site laboratory.

resultsPathways using a POC NAAT for asymptomatic and symptomatic patients and chlamydia/gonorrhoea-only tests were shorter and less expensive than most of the current pathways. Notably, we estimate that POC testing as part of a sexual health screen for symptomatic patients, or as stand-alone chlamydia/gonorrhoea testing, could reduce costs per patient by as much as £16 or £6, respectively. In both cases, healthcare professionals' time would be reduced by approximately 10 min per patient.

conclusionsPOC testing for chlamydia/gonorrhoea in a clinical setting may reduce costs and clinician time, and may lead to more appropriate and quicker care for patients. Further study is warranted on how to best implement POC testing in clinics, and on the broader clinical and cost implications of this technology.

Indexed as

Health Care CostsAmbulatory Care FacilitiesChlamydia InfectionsCritical PathwaysFemaleGonorrheaHealth ResourcesHumansMaleNucleic Acid Amplification TechniquesPoint-of-Care SystemsPoint-of-Care TestingReproductive Tract InfectionsUnited KingdomUrinary Tract InfectionsGenitourinary MedicineHealth EconomicsHealth Services Administration & ManagementSexual Medicine

Identifiers

PMID25056977
PMCPMC4120370
OpenAlexW2069659506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.