Evidence map›Paper›PMID 25056973›Full record

ArticleBMJ open2014

Brazilian medicinal plants to treat upper respiratory tract and bronchial illness: systematic review and meta-analyses-study protocol.

Luciane C Lopes, Maria Carolina O Silva, Cristiane Bergamashi Motta, Antonio Macho Quirós, Maique Weber Biavatti, Jardel Corrêa de Oliveira, Gordon Guyatt

Abstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synergistic Antimicrobial Effects of CefabronchinEuropean journal of microbiology & immunology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luciane C LopesPharmaceutical Sciences Post graduate Course, University of Sorocaba, UNISO, Sorocaba, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0002-3684-3275
Maria Carolina O SilvaPharmaceutical Sciences Post graduate Course, University of Sorocaba, UNISO, Sorocaba, Sao Paulo, Brazil.
Cristiane Bergamashi MottaPharmaceutical Sciences Post graduate Course, University of Sorocaba, UNISO, Sorocaba, Sao Paulo, Brazil.
Antonio Macho QuirósBiología Celular, Fisiología e Inmunología. Facultad de Medicina, Universidad de Córdoba, Cordoba, Spain.
Maique Weber BiavattiPharmaceutical Department, Federal University of Florianopolis, Santa Catarina, Brazil.
Jardel Corrêa de OliveiraMédico de Família e Comunidade, Especialista em Saúde da Família, Geriatria e Gerontologia, Secretaria Municipal de Saúde, Florianópolis, Santa Catarina, Brazil.
Gordon GuyattDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRespiratory illness, often associated with cough and sputum, is frequent. In Brazil, herbal medicines are often recommended as a first-line treatment for respiratory illness. There exists uncertainty regarding the effectiveness of these treatments. No systematic review has evaluated Brazilian medicinal plants (BMP) to treat upper respiratory tract and bronchial illness (URTI). METHODS AND ANALYSIS: We will conduct a systematic review and, if appropriate, a series of meta-analyses evaluating the safety and effectiveness of BMP for URTI. Eligible randomised controlled trials and observational studies will enrol adult or paediatric patients presenting with URTI treated by BMP approved by the Brazilian Health Surveillance Agency compared with placebo, no treatment or an alternative therapy. Our search will include the Cochrane Central Register of Controlled Trials (CENTRAL), which contains the Cochrane Acute Respiratory Illness Group's Specialized Register; MEDLINE; EMBASE; CINAHL (Cumulative Index to Nursing and Allied Health Literature); Web of Science; AMED; LILACS; CAB abstracts; clinical trial.gov; the WHO Trial Register and the Brazilian thesis database (CAPES) without any language restrictions. Outcomes of interest are time to resolution of clinical symptoms and/or signs (cough, sputum production or activity limitations), severity of symptoms prior to resolution and major/minor adverse events. Teams of reviewers will, independently and in duplicate, screen titles and abstracts and the complete full text to determine eligibility. For eligible studies, reviewers will perform data abstraction and assess risk of bias of eligible trials. When appropriate, we will conduct meta-analyses. We will also assess the quality of body of evidence (confidence in estimates of effect) for each of the outcomes using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. ETHICS AND DISSEMINATION: The systematic review will be published in a peer-reviewed journal. Brief reports of review findings will be disseminated directly to appropriate audiences via email and other modes of communication. The review will guide healthcare practice and policy in Brazil. TRIAL REGISTRATION NUMBER: Prospero CRD42014007057.

Indexed as

PhytotherapyPlants, MedicinalBrazilBronchial DiseasesHumansMeta-Analysis as TopicObservational Studies as TopicRandomized Controlled Trials as TopicResearch DesignRespiratory Tract DiseasesSystematic Reviews as TopicComplementary MedicineRespiratory Medicine (see Thoracic Medicine)Therapeutics

Identifiers

PMID25056973
PMCPMC4120431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.