ArticleJournal of virology2014
Virome analysis of Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis ticks reveals novel highly divergent vertebrate and invertebrate viruses.
Article in Journal of virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
124 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.
- Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review.Parasites & vectors · 2016Pooled it
- Characterization of a novel Iflavirus from the locust Calliptamus italicus in Xinjiang, China.Virus genes · 2026Article
- Metagenomic analysis of the midgut microbiome in Dermacentor abaensis ticks at different feeding states.Experimental & applied acarology · 2026Article
- Tick-borne viruses: discovery, clinical aspects, influencing factors and control.Nature reviews. Microbiology · 2026Review
- Tick Microbiome and Its Role in Emerging Zoonotic Diseases and Transmissibility.Microorganisms · 2026Review
- RNA virome of ticks and fleas infesting Marmota himalayana from the Qinghai-Tibet plateau.Animal microbiome · 2025Article
- A Field Study Examining the Attraction of AdultPathogens (Basel, Switzerland) · 2025Article
- Virome profiling of Culex tarsalis through small RNA-seq: A challenge of suboptimal samples.PLoS neglected tropical diseases · 2025Article
- Emerging tick-borne diseases in mainland China over the past decade: a systematic review and mapping analysis.The Lancet regional health. Western Pacific · 2025Article
- Exploring the potential of tick transcriptomes for virus screening: A data reuse approach for tick-borne virus surveillance.PLoS neglected tropical diseases · 2025Article
- Detection of novel coltivirus-related sequences in Haemaphysalis megaspinosa ticks collected from Kanagawa Prefecture, Japan.The Journal of veterinary medical science · 2024Article
- RNA viromes of Dermacentor nuttalli ticks reveal a novel uukuvirus in Qīnghăi Province, China.Virologica Sinica · 2024Article
- Virome diversity shaped by genetic evolution and ecological landscape of Haemaphysalis longicornis.Microbiome · 2024Article
- Characterisation of putative novel tick viruses and zoonotic risk prediction.Ecology and evolution · 2024Article
- Tick-Borne Co-Infections: Challenges in Molecular and Serologic Diagnoses.Pathogens (Basel, Switzerland) · 2023Review
- RNA Viruses Are Prevalent and Active Tenants of the Predatory Mite Phytoseiulus persimilis (Acari: Phytoseiidae).Microbial ecology · 2023Article
- Diversity of the Bacterial and Viral Communities in the Tropical Horse Tick,Pathogens (Basel, Switzerland) · 2023Article
- Multiomics Reveals Symbionts, Pathogens, and Tissue-Specific Microbiome of Blacklegged Ticks (Ixodes scapularis) from a Lyme Disease Hot Spot in Southeastern Ontario, Canada.Microbiology spectrum · 2023Article
- Diversification of Bourbon Virus in New York State.Microorganisms · 2023Article
- Diversity of the bacterial and viral communities in the tropical horse tick,bioRxiv : the preprint server for biology · 2023Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
unlabelledA wide range of bacterial pathogens have been identified in ticks, yet the diversity of viruses in ticks is largely unexplored. In the United States, Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis are among the principal tick species associated with pathogen transmission. We used high-throughput sequencing to characterize the viromes of these tick species and identified the presence of Powassan virus and eight novel viruses. These included the most divergent nairovirus described to date, two new clades of tick-borne phleboviruses, a mononegavirus, and viruses with similarity to plant and insect viruses. Our analysis revealed that ticks are reservoirs for a wide range of viruses and suggests that discovery and characterization of tick-borne viruses will have implications for viral taxonomy and may provide insight into tick-transmitted diseases. IMPORTANCE: Ticks are implicated as vectors of a wide array of human and animal pathogens. To better understand the extent of tick-borne diseases, it is crucial to uncover the full range of microbial agents associated with ticks. Our current knowledge of the diversity of tick-associated viruses is limited, in part due to the lack of investigation of tick viromes. In this study, we examined the viromes of three tick species from the United States. We found that ticks are hosts to highly divergent viruses across several taxa, including ones previously associated with human disease. Our data underscore the diversity of tick-associated viruses and provide the foundation for further studies into viral etiology of tick-borne diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.