Evidence map›Paper›PMID 25056884›Full record

ArticleJournal of virology2014

Stability determinants of murine cytomegalovirus long noncoding RNA7.2.

Toni M Schwarz, Caroline A Kulesza

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Roles of LncRNAs in Viral Infections.Frontiers in cellular and infection microbiology · 2017
    Review
  7. Long noncoding RNAs in innate immunity.Cellular & molecular immunology · 2016
    Review
  8. Viral noncoding RNAs: more surprises.Genes & development · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Toni M SchwarzDepartment of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Caroline A KuleszaDepartment of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA carolinekuleszaphd@gmail.com.
University of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus is a ubiquitous herpesvirus that persistently replicates in glandular epithelial tissue. Murine cytomegalovirus expresses a 7.2-kb-long noncoding RNA (RNA7.2) that is a determinant of viral persistence in the salivary gland. RNA7.2 is an extremely long-lived intron, yet the basis of its stability is unknown. We present data that localize key sequence determinants of RNA stability to the 3' end of RNA7.2 and suggest that stability is a result of sustained lariat conformation.

Indexed as

RNA StabilityAnimalsBase SequenceHerpesviridae InfectionsIntronsMiceMolecular Sequence DataMuromegalovirusNucleic Acid ConformationRNA, Long NoncodingRNA, ViralSalivary GlandsVirus ReplicationRNA, Long NoncodingRNA, Viral

Identifiers

PMID25056884
PMCPMC4178805
OpenAlexW2070316074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.