Evidence map›Paper›PMID 25056392›Full record

ReviewClinical pharmacology and therapeutics2014

CYP2D6 genotype and tamoxifen: considerations for proper nonprospective studies.

M P Goetz, J N Ingle

Abstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Metabolic Pathway Analysis and Effectiveness of Tamoxifen in Danish Breast Cancer Patients.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  7. Observational
  8. Article
  9. Article
  10. Endocrine resistance in breast cancer--An overview and update.Molecular and cellular endocrinology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M P Goetz1] Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA [2] Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.
J N IngleDepartment of Oncology, Mayo Clinic, Rochester, Minnesota, USA.

Funding

The Role of CHFR in Tumorigenesis and Paclitaxel-Sensitivity in Breast CancerP50CA116201 · NCI · MAYO CLINIC ROCHESTER · PI PETER C LUCAS · 2005 to 2026
$49.9M
Tamoxifen biotransformation pathway pharmacogenomicsR01CA133049 · NCI · MAYO CLINIC ROCHESTER · PI GOETZ, MATTHEW PHILIP · 2008 to 2013
$2.3M
NCI NIH HHS 1R01CA133049-01NCI NIH HHS CA116201NCI NIH HHS P50 CA116201NCI NIH HHS R01 CA133049
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GenotypeAntineoplastic Agents, HormonalCytochrome P-450 CYP2D6HumansNeoplasmsRandomized Controlled Trials as TopicTamoxifenAntineoplastic Agents, HormonalCytochrome P-450 CYP2D6Tamoxifen

Identifiers

PMID25056392
PMCPMC4167684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.