Evidence map›Paper›PMID 25056364›Full record

Trial reportClinical and vaccine immunology : CVI2014

A new modified live porcine reproductive and respiratory syndrome vaccine improves growth performance in pigs under field conditions.

Changhoon Park, Hwi Won Seo, Ikjae Kang, Jiwoon Jeong, Kyuhyung Choi, Chanhee Chae

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical and vaccine immunology : CVI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Comparison of 3 vaccination strategies against porcine reproductive and respiratory syndrome virus,Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Changhoon ParkDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Hwi Won SeoDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Ikjae KangDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Jiwoon JeongDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Kyuhyung ChoiDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Chanhee ChaeDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea swine@snu.ac.kr.
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The change in growth performance resulting from a new modified live porcine reproductive and respiratory syndrome (PRRS) vaccine was evaluated under field conditions for registration with the government as guided by the Republic of Korea's Animal and Plant Quarantine Agency. Three farms were selected based on their history of PRRS-associated respiratory diseases. On each farm, a total of 45 3-week-old pigs were randomly allocated to one of two treatment groups, (i) vaccinated (n = 25) or (ii) control (n = 20) animals. A new modified live PRRSV vaccine increased market weight by 1.26 kg/pig (104.71 kg versus 103.45 kg; P < 0.05) and decreased mortality by 17% (1.33% versus 18.33%; P < 0.05). Pathological examination indicated that vaccination effectively reduced microscopic lung lesions compared with control animals on the 3 farms. Thus, the new modified live PRRS vaccine improved growth performance and decreased mortality and lung lesions when evaluated under field conditions.

Indexed as

AnimalsBody WeightHistocytochemistryLungMicroscopyMolecular Sequence DataPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusRepublic of KoreaRNA, ViralSequence Analysis, DNASurvival AnalysisSwineTreatment OutcomeVaccines, AttenuatedViral VaccinesRNA, ViralVaccines, AttenuatedViral Vaccines

Identifiers

PMID25056364
PMCPMC4178575
OpenAlexW2324529419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.