ArticleMycopathologia2014
Candidaemia observed at a university hospital in Milan (northern Italy) and review of published studies from 2010 to 2014.
Article in Mycopathologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 27 citations in OpenAlex.
- Species-Specific Sensitivity and Levels of Beta-D-Glucan for the Diagnosis of Candidemia-A Systematic Review and Meta-Analysis.Journal of fungi (Basel, Switzerland) · 2025Review
- Candidemia in Internal Medicine: Facing the New Challenge.Mycopathologia · 2022Article
- Active Flavonoids fromMolecules (Basel, Switzerland) · 2021Article
- Article
- Clinical and Laboratory Development of Echinocandin Resistance inFrontiers in microbiology · 2019Article
- Article
- Correlation between antifungal consumption and the distribution of Candida species in different hospital departments of a Lebanese medical Centre.BMC infectious diseases · 2018Article
- Article
- Evaluation of candidemia and antifungal consumption in a large tertiary care Italian hospital over a 12-year period.Infection · 2018Article
- Article
- Azole Resistance in Candida glabrata.Current infectious disease reports · 2016Review
- Nosocomial Bloodstream Infection Due to Candida spp. in China: Species Distribution, Clinical Features, and Outcomes.Mycopathologia · 2016Article
- First description of Candida nivariensis in Brazil: antifungal susceptibility profile and potential virulence attributes.Memorias do Instituto Oswaldo Cruz · 2016Article
- Azole Antifungal Resistance inFrontiers in microbiology · 2016Review
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandida species represent the fourth leading cause of nosocomial bloodstream infections (BSI) worldwide. However, candidaemia rates and species involved vary geographically.
objectivesTo evaluate the epidemiological pattern, risk factors for mortality and antifungal therapy of Candida BSI over a 5-year period (2008-2012) in a university hospital in northern Italy together with a review of the recent literature concerning candidaemia.
methodsA retrospective cohort study cross-linked with microbiology database was performed.
resultsA total of 89 Candida BSI were identified in 42 males (47 %) and 47 females (52.8 %). The median age was 69 years (interquartile range 55-78) with 61.8 % of patients being older than 65 years. Considering all hospitalized patients, the overall incidence rate of candidaemia increased significantly from 2008 to 2012 (from 0.4 to 1.68 episodes per 10,000 patient/days) (p = 0.0001) with a mean linear increase in 5 new cases per year. Candida albicans was the predominant species isolated (64 %) followed by C. glabrata (19.1 %). The latter species was observed with significantly higher frequency in Internal Medicine and Intensive Care Units (ICU). In-hospital crude mortality was 41.6 %.
conclusionsCandidaemia is an increasing BSI in our university hospital, in accordance with that observed in northern Italy, and it is still associated with high in-hospital crude mortality.
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