ArticleChemistry (Weinheim an der Bergstrasse, Germany)2014
Efficient asymmetric synthesis of 1-cyano-tetrahydroisoquinolines from lipase dual activity and opposite enantioselectivities in α-Aminonitrile resolution.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Lipase-Catalyzed Strategies for the Preparation of Enantiomeric THIQ and THMolecules (Basel, Switzerland) · 2023Review
- Dynamic Covalent Kinetic Resolution.Catalysis reviews, science and engineering · 2020Article
- Enzyme classification using complex dynamic hemithioacetal systems.Chemical communications (Cambridge, England) · 2016Article
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Authors and funding
3 authors.
Funding
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Abstract
Dual promiscuous racemization/amidation activities of lipases leading to efficient dynamic kinetic resolution protocols of racemic α-aminonitrile compounds are described. α-Amidonitrile products of high enantiomeric purity could be formed in high yields. Several lipases from different sources were shown to exhibit the dual catalytic activities, where opposite enantioselectivities could be recorded for certain substrates.
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