ArticleGenes2014
From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.
Article in Genes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Diurnal dynamics of different circadian transcription modules in Chinese pine needles and roots during dormancy induction.BMC plant biology · 2025Article
- Serum metabolic characteristics associated with the deterioration of colorectal adenomas.Scientific reports · 2025Article
- Insight into Fructose-to-Sucrose Ratio as the Potential Target of Urinalysis in Bladder Cancer.Metabolites · 2024Article
- CircRNAs: emerging factors for regulating glucose metabolism in colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Review
- Predicting ecosystem metaphenome from community metagenome: A grand challenge for environmental biology.Ecology and evolution · 2023Article
- A Comprehensive Metabolomics Analysis of Fecal Samples from Advanced Adenoma and Colorectal Cancer Patients.Metabolites · 2022Article
- An 11-gene signature for the prediction of systemic recurrences in colon adenocarcinoma.Gastroenterology report · 2021Article
- Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer.International journal of molecular sciences · 2021Review
- A novel epithelial-mesenchymal transition molecular signature predicts the oncological outcomes in colorectal cancer.Journal of cellular and molecular medicine · 2021Article
- Untargeted Metabolomics Reveals Major Differences in the Plasma Metabolome between Colorectal Cancer and Colorectal Adenomas.Metabolites · 2021Article
- Comprehensive Transcriptomic Analysis Reveals Prognostic Value of an EMT-Related Gene Signature in Colorectal Cancer.Frontiers in cell and developmental biology · 2021Article
- Identification of a Novel Immune-Related CpG Methylation Signature to Predict Prognosis in Stage II/III Colorectal Cancer.Frontiers in genetics · 2021Article
- Serum lipidome screening in patients with stage I non-small cell lung cancer.Clinical and experimental medicine · 2019Article
- Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research.Cancers · 2019Review
- Article
- Cancer metabolomic markers in urine: evidence, techniques and recommendations.Nature reviews. Urology · 2019Review
- Development and Validation of an Autophagy Score Signature for the Prediction of Post-operative Survival in Colorectal Cancer.Frontiers in oncology · 2019Article
- A robust gene signature for the prediction of early relapse in stage I-III colon cancer.Molecular oncology · 2018Article
- A novel gene-pair signature for relapse-free survival prediction in colon cancer.Cancer management and research · 2018Article
- Progress in Metabolomics Standardisation and its Significance in Future Clinical Laboratory Medicine.EJIFCC · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Much effort in recent years has been expended in defining the genomic and epigenetic alterations that characterize colorectal adenocarcinoma and its subtypes. However, little is known about the functional ramifications related to various subtypes. Metabolomics, the study of small molecule intermediates in disease, provides a snapshot of the functional phenotype of colorectal cancer. Data, thus far, have characterized some of the metabolic perturbations that accompany colorectal cancer. However, further studies will be required to identify biologically meaningful metabolic subsets, including those corresponding to specific genetic aberrations. Moreover, further studies are necessary to distinguish changes due to tumor and the host response to tumor.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.