Evidence map›Paper›PMID 25054749›Full record

ReviewAnais brasileiros de dermatologia

Effects of low-power light therapy on wound healing: LASER x LED.

Maria Emília de Abreu Chaves, Angélica Rodrigues de Araújo, André Costa Cruz Piancastelli, Marcos Pinotti

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06623305 (Photobiomodulation Therapy for the Prevention of Mucositis in Pediatric Oncology Patients), which is not on this map. Cited by 94 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 4 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06623305 nanot yet recruitingnot on this map

Photobiomodulation Therapy for the Prevention of Mucositis in Pediatric Oncology Patients

TypeinterventionalSponsorMedical College of WisconsinRan2026 to 2027Enrolled50ConditionsMucositis OralArmsPhotobiomodulation for prevention arm, Photobiomodulation for exploratory arm
3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 4 syntheses or guidelines pooled it, 274 citations in OpenAlex.

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  13. Low-power infrared laser on telomere maintenance in an experimental model of arthritis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Maria Emília de Abreu ChavesUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Angélica Rodrigues de AraújoPontifícia Universidade Católica de Minas Gerais, Belo Horizonte, MG, Brazil.
André Costa Cruz PiancastelliServiço de Dermatologia, Hospital da Polícia Militar, Belo Horizonte, MG, Brazil.
Marcos PinottiUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Universidade Federal de Minas Gerais · BRHospital Central da Polícia Militar · BRPontifícia Universidade Católica de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies demonstrate the benefits of low-power light therapy on wound healing. However, the use of LED as a therapeutic resource remains controversial. There are questions regarding the equality or not of biological effects promoted by LED and LASER. One objective of this review was to determine the biological effects that support the use of LED on wound healing. Another objective was to identify LED´s parameters for the treatment of wounds. The biological effects and parameters of LED will be compared to those of LASER. Literature was obtained from online databases such as Medline, PubMed, Science Direct and Scielo. The search was restricted to studies published in English and Portuguese from 1992 to 2012. Sixty-eight studies in vitro and in animals were analyzed. LED and LASER promote similar biological effects, such as decrease of inflammatory cells, increased fibroblast proliferation, stimulation of angiogenesis, granulation tissue formation and increased synthesis of collagen. The irradiation parameters are also similar between LED and LASER. The biological effects are dependent on irradiation parameters, mainly wavelength and dose. This review elucidates the importance of defining parameters for the use of light devices.

Indexed as

Dose-Response Relationship, RadiationHumansLasers, SemiconductorLow-Level Light TherapyReference ValuesSkinWound Healing

Identifiers

PMID25054749
PMCPMC4148276
OpenAlexW2058244038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.