ArticleMolecular and clinical oncology2014
Characterization of lymph node metastasis and its clinical significance in the surgical treatment of gastric cancer.
Article in Molecular and clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Association between primary tumor location and lymph node metastatic patterns in gastric cancer: A single-center retrospective study.Medicine · 2026Article
- Development and temporal validation of preoperative and combined preoperative-pathological models for lymph node metastasis in early gastric cancer.Frontiers in oncology · 2026Article
- Article
- Application of machine learning algorithms to predict lymph node metastasis in gastric neuroendocrine neoplasms.Heliyon · 2023Article
- Distribution of splenic artery lymph nodes and splenic hilar lymph nodes.World journal of gastrointestinal surgery · 2023Article
- Review
- Characteristics and Prognosis of Acquired Resistance to Immune Checkpoint Inhibitors in Gastrointestinal Cancer.JAMA network open · 2022Article
- Apatinib inhibits gastric carcinoma development by regulating the expression levels of IL-17 via the Bax/Bcl-2 signaling pathway.Experimental and therapeutic medicine · 2021Article
- Laparoscopic infrapyloric lymph nodes dissection through the right bursa omentalis approach for gastric cancer.BMC surgery · 2021Article
- A Substage Increase in The AJCC Classification System Improves Prognostic Prediction in Stage III Gastric Cancer With Insufficient Lymph Nodes Removed.Frontiers in oncology · 2021Article
- Risk Factors of Lymph Node Metastasis and Its Prognostic Significance in Early Gastric Cancer: A Multicenter Study.Frontiers in oncology · 2021Article
- Variations of Gastrocolic Trunk of Henle and Its Significance in Gastrocolic Surgery.Gastroenterology research and practice · 2018Review
- The prognostic value of negative lymph node count for patients with gastric cancer who received preoperative radiotherapy.Oncotarget · 2017Article
- A pilot study of lymph node mapping with indocyanine green in robotic gastrectomy for gastric cancer.SAGE open medicine · 2017Article
- N staging: the role of the pathologist.Translational gastroenterology and hepatology · 2017Review
- Clinical significance of lymphadenectomy in patients with gastric cancer.World journal of gastrointestinal oncology · 2016Review
- The Impact of Confluence Types of the Right Gastroepiploic Vein on No. 6 Lymphadenectomy During Laparoscopic Radical Gastrectomy.Medicine · 2015Observational
- Risk factors associated with splenic hilar lymph node metastasis in patients with advanced gastric cancer in northwest China.International journal of clinical and experimental medicine · 2015Article
- Angiolymphatic invasion as a prognostic fator in resected N0 pancreatic adenocarcinoma.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgeryArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to characterize lymph node metastasis and determine its clinical significance in the surgical treatment of gastric cancer. The medical charts of 920 gastric cancer patients who underwent radical surgical resection between March, 2010 and March, 2013, were retrospectively reviewed and statistically analyzed. Lymphatic metastasis was observed in 69.6% of the patients (640/920). The frequency of lymph node metastasis in patients with early-stage gastric cancer was 21.4% (18/84). Lymph node metastasis was observed in all the patients with stage IIIC-IV gastric cancer. The incidence of lymph node metastasis was higher among patients with tumors >7 cm in size. The most frequently affected lymph nodes in patients with proximal, central and distal gastric cancer were station no. 1 (34.2%), no. 3 (33.8%) and no. 6 (34.3%) lymph nodes, respectively. The frequency of lymph node metastasis in patients with Borrmann type IV cancer was significantly higher compared to that in patients with other Borrmann type cancers. Our study further demonstrated that lymphatic metastasis is closely correlated with TNM stage, location, depth of invasion and size of gastric tumors. Therefore, we recommend that a sufficient number of lymph nodes be examined from each patient to determine the extent of lymph node dissection based on Borrmann type, location, size, depth of invasion and histology of the cancer.
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