Evidence map›Paper›PMID 25054017›Full record

ArticleBiomedical reports2014

Single-nucleotide polymorphism (c.309T>G) in the

Yasuaki Enokida, Kimihiro Shimizu, Seiichi Kakegawa, Jun Atsumi, Yoshiaki Takase, Yohei Miyamae, Toshiteru Nagashima, Yoichi Ohtaki, Kyoichi Kaira, Noriaki Sunaga and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Interaction between common variants ofAnnals of translational medicine · 2020
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Yasuaki EnokidaDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Kimihiro ShimizuDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Seiichi KakegawaDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Jun AtsumiDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Yoshiaki TakaseDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Yohei MiyamaeDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Toshiteru NagashimaDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Yoichi OhtakiDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Kyoichi KairaDepartment of Oncology Clinical Development, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Noriaki SunagaDepartment of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Noriko YanagitaniDepartment of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Reiko YoshinoDepartment of Internal Medicine, National Hospital Organization Nishi-Gunma Hospital, Shibukawa, Gunma 377-8511, Japan.
Katsuhiko TsunekawaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Hitoshi IgaiDepartment of General Thoracic Surgery, Maebashi Red Cross Hospital, Maebashi, Gunma 371-0014, Japan.
Mitsuhiro KamiyoshiharaDepartment of General Thoracic Surgery, Maebashi Red Cross Hospital, Maebashi, Gunma 371-0014, Japan.
Kengo UsuiDivision of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Kanagawa 230-0045, Japan.
Alexander LezhavaDivision of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Kanagawa 230-0045, Japan.
Yoshio TomizawaDepartment of Internal Medicine, National Hospital Organization Nishi-Gunma Hospital, Shibukawa, Gunma 377-8511, Japan.
Toshihisa IshikawaNGO Personalized Medicine and Healthcare, Yokohama, Kanagawa 226-0016, Japan.
Masami MurakamiDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Yoshihide HayashizakiRIKEN Preventive Medicine and Diagnosis Innovation Program, Yokohama, Kanagawa 230-0045, Japan.
Izumi TakeyoshiDepartment of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan.
Gunma University · JPMaebashi Red Cross Hospital · JPNational Hospital Organization · JPRIKEN Center for Integrative Medical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Murine double minute 2 (MDM2) is a negative regulator of p53. A single-nucleotide polymorphism (SNP) (rs2279744: c.309T>G) in the promoter region of the

Indexed as

cancer susceptibilitylung cancermurine double minute 2p53single-nucleotide polymorphism 309smart amplification processsmoking history

Identifiers

PMID25054017
PMCPMC4106610
OpenAlexW1974548330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.