ArticleBiomedical reports2014
Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: A meta-analysis of 10,415 subjects.
Article in Biomedical reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Genetic Variants in the MTHFR and WNK1 Genes and Their Contribution to Hypertension Susceptibility.International journal of medical sciences · 2026Article
- Article
- Revitalising Riboflavin: Unveiling Its Timeless Significance in Human Physiology and Health.Foods (Basel, Switzerland) · 2024Review
- Association study between genetic polymorphisms in MTHFR and stroke susceptibility in Egyptian population: a case-control study.Scientific reports · 2024Article
- Targeting Homocysteine and Hydrogen Sulfide Balance as Future Therapeutics in Cancer Treatment.Antioxidants (Basel, Switzerland) · 2023Review
- Susceptibility to hypertension based onFrontiers in cardiovascular medicine · 2023Article
- Juvenile patients with the homozygous MTHFR C677T genotype develop ischemic stroke 5 years earlier than wild type.Journal of thrombosis and thrombolysis · 2022Article
- Review
- Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis.Cardiovascular therapeutics · 2022Article
- Association BetweenFrontiers in genetics · 2021Review
- Article
- Methylenetetrahydrofolate Reductase C677T Gene Polymorphism as a Risk Factor for Hypertension in a Rural Population.International journal of hypertension · 2020Article
- Evidence of a Role for One-Carbon Metabolism in Blood Pressure: Can B Vitamin Intervention Address the Genetic Risk of Hypertension Owing to a Common Folate Polymorphism?Current developments in nutrition · 2020Review
- Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population.International journal of hypertension · 2020Article
- The Role of Polymorphism GenOpen access Macedonian journal of medical sciences · 2019Article
- Plasmatic Concentrations of ADMA and Homocystein in Llama (Frontiers in physiology · 2018Article
- Dietary Reference Values for riboflavin.EFSA journal. European Food Safety Authority · 2017Article
- Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing.Nutrients · 2016Review
- Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure.Nutrients · 2016Review
- Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco.BMC research notes · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The methylenetetrahydrofolate reductase (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.