Evidence map›Paper›PMID 25053905›Full record

ArticleKorean journal of radiology

Contrast-induced nephropathy in patients undergoing intravenous contrast-enhanced computed tomography in Korea: a multi-institutional study in 101487 patients.

Joongyub Lee, Jeong Yeon Cho, Hak Jong Lee, Yong Yeon Jeong, Chan Kyo Kim, Byung Kwan Park, Deuk Jae Sung, Byung Chul Kang, Sung Il Jung, Eun Ju Lee and 13 more

Abstract readMulticenter Study
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Joongyub LeeMedical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-799, Korea.
Jeong Yeon ChoDepartment of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 110-744, Korea. ; Kidney Research Institute, Seoul National University Medical Research Center, Seoul 110-744, Korea.
Hak Jong LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Yong Yeon JeongDepartment of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun 519-763, Korea.
Chan Kyo KimDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
Byung Kwan ParkDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
Deuk Jae SungDepartment of Radiology, Anam Hospital, Korea University College of Medicine, Seoul 136-705, Korea.
Byung Chul KangDepartment of Radiology, Ewha Womans University Medical Center, Seoul 158-710, Korea.
Sung Il JungDepartment of Radiology, Konkuk University Medical Center, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 143-729, Korea.
Eun Ju LeeDepartment of Radiology, Ajou University School of Medicine, Suwon 443-721, Korea.
Boem-Ha YiDepartment of Diagnostic Radiology, Soonchunhyang University Bucheon Hospital, Bucheon 420-767, Korea.
Seong Jin ParkDepartment of Diagnostic Radiology, Soonchunhyang University Bucheon Hospital, Bucheon 420-767, Korea. ; Department of Radiology, Kyung Hee University Hospital, Seoul 130-702, Korea.
Jong Chul KimDepartment of Radiology, Chungnam National University School of Medicine, Daejeon 301-721, Korea.
Dae Chul JungDepartment of Radiology, Yonsei University College of Medicine, Severance Hospital, Seoul 120-752, Korea. ; Department of Radiology, National Cancer Center, Goyang 410-769, Korea.
Chang-Kyu SungDepartment of Radiology, Seoul National University Boramae Hospital, Seoul 156-707, Korea.
Yongsoo KimDepartment of Radiology, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri 471-701, Korea.
Youngrae LeeDepartment of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, Korea.
Sun Ho KimDepartment of Radiology, National Cancer Center, Goyang 410-769, Korea. ; Department of Radiology, Dongguk University Ilsan Hospital, Goyang 410-773, Korea.
Seong Kuk YoonDepartment of Radiology, College of Medicine, Dong-A University, Busan 602-714, Korea.
Byung-Joo ParkMedical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Korea Institute of Drug Safety and Risk Management, Seoul 110-750, Korea. ; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Seung Hyup KimDepartment of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 110-744, Korea. ; Kidney Research Institute, Seoul National University Medical Research Center, Seoul 110-744, Korea.
Korean Society of Urogenital Radiology (KSUR)
Korean Society of Radiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the prevalence of known risk factors for contrast-induced nephropathy (CIN) and their association with the actual occurrence of CIN in patients undergoing intravenous contrast-enhanced computed tomography (CECT) in Korea. MATERIALS AND

methodsPatients who underwent CECT in 2008 were identified in the electronic medical records of 16 tertiary hospitals of Korea. Data on demographics, comorbidities, prescriptions and laboratory test results of patients were collected following a standard data extraction protocol. The baseline renal function was assessed using the estimated glomerular filtration rate (eGFR). We identified the prevalence of risk factors along the eGFR strata and evaluated their influence on the incidence of CIN, defined as a 0.5 mg/dL or 25% increase in serum creatinine after CECT.

resultsOf 432425 CECT examinations in 272136 patients, 140838 examinations in 101487 patients met the eligibility criteria for analysis. The mean age of the participants was 57.9 ± 15.5 years; 25.1% of the patients were older than 70 years. The prevalence of diabetes mellitus was 11.9%, of hypertension 13.7%, of gout 0.55% and of heart failure was 1.7%. Preventive measures were used in 40238 CECT examinations (28.6%). The prevalence of risk factors and use of preventive measures increased as the renal function became worse. A CIN was occurred after 3103 (2.2%) CECT examinations, revealing a significant association with decreased eGFR, diabetes mellitus, and congestive heart failure after adjustment.

conclusionRisk factors for CIN are prevalent among the patients undergoing CECT. Preventive measures were seemingly underutilized and a system is needed to improve preventive care.

Indexed as

AdultAgedAged, 80 and overComorbidityContrast MediaFemaleGlomerular Filtration RateHumansIncidenceKidney DiseasesMaleMiddle AgedPrevalenceRepublic of KoreaRisk FactorsTomography, X-Ray ComputedContrast MediaContrast-enhanced computed tomographyContrast-induced nephropathyPrevalenceRisk factor

Identifiers

PMID25053905
PMCPMC4105808

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.