Evidence map›Paper›PMID 25052854›Full record

ArticlePlant physiology2014

Long-term evolution of nucleotide-binding site-leucine-rich repeat genes: understanding gained from and beyond the legume family.

Zhu-Qing Shao, Yan-Mei Zhang, Yue-Yu Hang, Jia-Yu Xue, Guang-Can Zhou, Ping Wu, Xiao-Yi Wu, Xun-Zong Wu, Qiang Wang, Bin Wang and 1 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhu-Qing ShaoState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Yan-Mei ZhangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Yue-Yu HangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Jia-Yu XueState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Guang-Can ZhouState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Ping WuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Xiao-Yi WuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Xun-Zong WuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Qiang WangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.).
Bin WangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.) binwang@nju.edu.cn chenjq@nju.edu.cn.
Jian-Qun ChenState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China (Z.-Q.S., Y.-M.Z., J.-Y.X., G.-C.Z., P.W., X.-Y.W., X.-Z.W., Q.W., B.W., J.-Q.C.); andJiangsu Province and Chinese Academy of Science, Institute of Botany, Nanjing 210014, China (Y.-M.Z., Y.-Y.H., J.-Y.X.) binwang@nju.edu.cn chenjq@nju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper utilization of plant disease resistance genes requires a good understanding of their short- and long-term evolution. Here we present a comprehensive study of the long-term evolutionary history of nucleotide-binding site (NBS)-leucine-rich repeat (LRR) genes within and beyond the legume family. The small group of NBS-LRR genes with an amino-terminal RESISTANCE TO POWDERY MILDEW8 (RPW8)-like domain (referred to as RNL) was first revealed as a basal clade sister to both coiled-coil-NBS-LRR (CNL) and Toll/Interleukin1 receptor-NBS-LRR (TNL) clades. Using Arabidopsis (Arabidopsis thaliana) as an outgroup, this study explicitly recovered 31 ancestral NBS lineages (two RNL, 21 CNL, and eight TNL) that had existed in the rosid common ancestor and 119 ancestral lineages (nine RNL, 55 CNL, and 55 TNL) that had diverged in the legume common ancestor. It was shown that, during their evolution in the past 54 million years, approximately 94% (112 of 119) of the ancestral legume NBS lineages experienced deletions or significant expansions, while seven original lineages were maintained in a conservative manner. The NBS gene duplication pattern was further examined. The local tandem duplications dominated NBS gene gains in the total number of genes (more than 75%), which was not surprising. However, it was interesting from our study that ectopic duplications had created many novel NBS gene loci in individual legume genomes, which occurred at a significant frequency of 8% to 20% in different legume lineages. Finally, by surveying the legume microRNAs that can potentially regulate NBS genes, we found that the microRNA-NBS gene interaction also exhibited a gain-and-loss pattern during the legume evolution.

Indexed as

Evolution, MolecularMultigene FamilyFabaceaeGene DeletionGene DuplicationGenome, PlantMicroRNAsPhylogenyMicroRNAs

Identifiers

PMID25052854
PMCPMC4149708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.