ReviewJournal of bioenergetics and biomembranes2014
The sodium pumping NADH:quinone oxidoreductase (Na⁺-NQR), a unique redox-driven ion pump.
Review in Journal of bioenergetics and biomembranes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 58 citations in OpenAlex.
- A Bacillales-specific tubular scaffold essential for NADH dehydrogenase activity.Nature communications · 2026Article
- Contrasting associations between microbiota respiratory strategies and seafloor macrofauna.ISME communications · 2026Article
- Machine learning-guided in Silico identification of Na⁺-NQR inhibitors from Berberis vulgaris and Hydrastis Canadensis phytochemicals against Vibrio cholerae.Scientific reports · 2025Article
- Diverse bacteriohemerythrin genes ofmBio · 2025Article
- Integrative microbiome- and metatranscriptome-based analyses reveal diagnostic biomarkers for peri-implantitis.NPJ biofilms and microbiomes · 2025Article
- Crp and Arc system directly regulate the transcription of NADH dehydrogenase genes inMicrobiology spectrum · 2025Article
- Unraveling diversity by isolating peptide sequences specific to distinct taxonomic groups.bioRxiv : the preprint server for biology · 2025Article
- Comparative genomics of symbioticMicrobial genomics · 2023Article
- The NQR Complex Regulates the Immunomodulatory Function of Bacteroides thetaiotaomicron.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Comparative Physiology and Genomics of Hydrogen-Producing Vibrios.Current microbiology · 2022Article
- Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance.Protein science : a publication of the Protein Society · 2022Article
- Microbial river-to-sea continuum: gradients in benthic and planktonic diversity, osmoregulation and nutrient cycling.Microbiome · 2021Article
- Article
- NamBio · 2020Article
- Article
- Research journey of respirasome.Protein & cell · 2020Review
- Metagenome-assembled genome distribution and key functionality highlight importance of aerobic metabolism in Svalbard permafrost.FEMS microbiology ecology · 2020Article
- Genetic and Biochemical Analysis of Anaerobic Respiration in Bacteroides fragilis and Its ImportancemBio · 2020Article
- Antibiotic Korormicin A Kills Bacteria by Producing Reactive Oxygen Species.Journal of bacteriology · 2019Article
- Occurrence and Function of the NaMicroorganisms · 2019Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Na(+)-translocating NADH:quinone oxidoreductase (Na(+)-NQR) is a unique Na(+) pumping respiratory complex found only in prokaryotes, that plays a key role in the metabolism of marine and pathogenic bacteria, including Vibrio cholerae and other human pathogens. Na(+)-NQR is the main entrance for reducing equivalents into the respiratory chain of these bacteria, catalyzing the oxidation of NADH and the reduction of quinone, the free energy of this redox reaction drives the selective translocation of Na(+) across the cell membrane, which energizes key cellular processes. In this review we summarize the unique properties of Na(+)-NQR in terms of its redox cofactor composition, electron transfer reactions and a possible mechanism of coupling and pumping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.