Evidence map›Paper›PMID 25052710›Full record

Trial reportEpilepsy research2014

Growth parameters and childhood epilepsy in Hai District, Tanzania: a community-based study.

Jane J Rogathe, Jim Todd, Ewan Hunter, Richard Walker, Antony Ngugi, Charles Newton, Kathryn Burton

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Epilepsy research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Jane J RogatheKilimanjaro Christian Medical University College, Moshi, Tanzania.
Jim ToddKilimanjaro Christian Medical University College, Moshi, Tanzania; National Institute for Medical Research, Mwanza, Tanzania.
Ewan HunterDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Tropical Medicine, London, UK.
Richard WalkerNorthumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, UK.
Antony NgugiCentre for Geographical Medice (Coast), Kenya Medical Research Institute, Kilifi, Kenya.
Charles NewtonDepartment of Paediatrics, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania; Department of Psychiatry, University of Oxford, Oxford, UK.
Kathryn BurtonNeurosciences Unit, Institute of Child Health, University College London, London, UK. Electronic address: kjburton@doctors.org.uk.
Kilimanjaro Christian Medical Centre · TZInstitute of Child Health · INKenya Medical Research Institute · KEMuhimbili University of Health and Allied Sciences · TZNorth Tyneside General Hospital · GB

Funding

Wellcome Trust 083744Wellcome Trust 095009
6 · The paper itself

Abstract

aimThis cross-sectional study examined whether growth parameters were associated with epilepsy in children living in a rural community in sub-Saharan Africa (SSA). MATERIALS AND

methodsA cross-sectional study was performed in the Hai District Demographic Surveillance Site (HDSS), Tanzania in which 6-14 year old children with epilepsy (CWE) were identified. Age matched controls were randomly selected from the Hai census database for comparison. Anthropometric measurements were used to assess the nutritional status of the children and body mass index (BMI) calculated. Associations between social, demographic and nutritional factors and epilepsy were assessed using multivariable logistic regression.

results112 CWE were identified and were compared with 113 controls. There was no significant difference in the BMI between cases and controls (T-test, p-value of 0.117). Amongst cases, there were no significant associations between BMI and motor difficulties, antiepileptic drug use, cognitive or behavioural problems, early-onset epilepsy or seizure frequency. In the whole group, BMI was significantly associated with socio-economic status (p=0.037) and age. DISCUSSION: There was no significant difference found between CWE and matched controls with respect to nutritional status. This suggests that there is no causal association between under nutrition and epilepsy in this community. Nutritional assessment is still important as part of the comprehensive care of CWE.

Indexed as

Body Mass IndexResidence CharacteristicsAdolescentAnticonvulsantsBody HeightChildCohort StudiesCross-Sectional StudiesEpilepsyFemaleHumansMaleRural PopulationTanzaniaAnticonvulsantsAfricaChildrenEpilepsyNutritional status

Identifiers

PMID25052710
PMCPMC5497074
OpenAlexW2049509232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.