SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2014
Risk of malignancy associated with head and neck CT in children: a systematic review.
Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Triage tools for detecting cervical spine injury in paediatric trauma patients.The Cochrane database of systematic reviews · 2024Pooled it
- Diagnostic yield of MRI for pediatric hearing loss: a systematic review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2015Pooled it
- Diagnostic yield of computed tomography scan for pediatric hearing loss: a systematic review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2014Pooled it
- Clinical and Radiological Characteristics of Pediatric Skull Fractures and Their Association with Neurosurgical Intervention: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- The Three-Dimensional Growth of Traumatic Intracerebral Hemorrhage in Patients with Abnormal Coagulation.Journal of neurological surgery. Part A, Central European neurosurgery · 2026Article
- Diffusion-Weighted MRI in Sinonasal Tumors: Diagnostic Insights From a Tertiary Center.Cureus · 2025Article
- Nasopharyngeal carcinoma in a 15-year-old: A rare pediatric tumor.Radiology case reports · 2025Article
- Observational
- Intratympanic Membrane Cholesteatoma in a Toddler.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Tau, Glial Fibrillary Acidic Protein, and Neurofilament Light Chain as Brain Protein Biomarkers in Cerebrospinal Fluid and Blood for Diagnosis of Neurobiological Diseases.International journal of molecular sciences · 2024Review
- Utility of brain imaging in pediatric patients with a suspected accidental spinal injury but no brain injury-related symptoms.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Comparison of Low-Dose Non-contrast CT in Detecting Anatomical and Surgically Important Variants of Paranasal Sinuses to Standard Dose Non-contrast CT: Experience from a Tertiary Care Hospital in Sub-Himalayan Region of Northern India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Clinical outcome following magnetic resonance imaging as first-line imaging in low-impact pediatric spine trauma: a single-center retrospective observational study.Pediatric radiology · 2023Observational
- Sudden onset headaches in paediatric emergency departments: diagnosis and management.Italian journal of pediatrics · 2023Review
- [Imaging after trauma in clinics and practice for children and adolescents : Part 1 of the results of a nationwide online survey of the Pediatric Traumatology Section of the German Trauma Society].Unfallchirurgie (Heidelberg, Germany) · 2023Article
- Development of an interdisciplinary microtia-atresia care model: A single-center 20-year experience.Laryngoscope investigative otolaryngology · 2022Article
- Understanding the harm of low-dose computed tomography radiation to the body (Review).Experimental and therapeutic medicine · 2022Review
- Imaging of Bone in the Head and Neck Region, is There More Than CT?Current radiology reports · 2022Review
- ALADA Dose Optimization in the Computed Tomography of the Temporal Bone: The Diagnostic Potential of Different Low-Dose CT Protocols.Diagnostics (Basel, Switzerland) · 2021Article
- Pediatric Nuclear Medicine Examinations and Subsequent Risk of Neoplasm: A Nationwide Population-Based Cohort Study.Frontiers in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo perform a systematic review to evaluate the risk of malignancy associated with computed tomography (CT) of the head and/or neck in infants, children, and adolescents. DATA SOURCES: Pubmed, EMBASE, and the Cochrane Library were assessed from the date of their inception to January 2014. Additionally, manual searches of bibliographies were performed and topic experts were contacted. REVIEW
methodsData were obtained from studies measuring or estimating the risks of malignancy associated with radiation from head and/or neck CT in pediatric populations according to an a priori protocol. Two independent evaluators corroborated the extracted data.
resultsThere were 16 criterion-meeting studies that included data from n = 858,815 patients. The radiation-related risk of malignancy was estimated using primary patient data for both the exposure and outcome in a minority of studies, with most analyses utilizing mathematical modeling techniques. The data regarding otolaryngology-specific studies were limited and suggested a borderline significant increase in the risk of all combined cancers after facial CT (incidence rate ratio [IRR] = 1.14; 95% CI, 1.01-1.28) and neck/spine CT (IRR = 1.13; 95% CI, 1.00-1.28). Cohort data suggest that 1 excess brain malignancy occurred after 4000 brain CTs (40 mSv per scan) and that the estimated risk in the 10 years following CT exposure was 1 brain tumor per 10,000 patients exposed to a 10 mGy scan at less than 10 years of age.
conclusionDetailed understanding of any potential malignancy risk associated with pediatric imaging of the head and neck furthers our ability to engage in rational, shared, informed decision making with families considering CT scan.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.