SynthesisCirculation2014
Sex differences in long-term mortality after myocardial infarction: a systematic review.
Synthesis in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy and safety of colchicine post myocardial infarction: a systematic review, meta-analysis and meta-regression analysis of randomized clinical trials.European journal of clinical pharmacology · 2025Pooled it
- Pooled it
- Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021Guideline
- Pooled it
- Sex differences in secondary preventive follow-up after coronary heart events.BMC cardiovascular disorders · 2023Trial
- Development of a novel tool: a nomogram for predicting in-hospital mortality of patients in intensive care unit after percutaneous coronary intervention.BMC anesthesiology · 2023Trial
- Sex disparities in the presentation, management and outcomes of patients with acute coronary syndrome: insights from the ACS QUIK trial.Open heart · 2021Trial
- High-Risk Comorbidities Drive Adverse Inpatient Outcomes After ERCP: A National Analysis and Predictive Model.Digestive diseases and sciences · 2026Article
- Sex- and race/ethnic differences in short- and long-term mortality after hospitalization for incident acute myocardial infarction.American heart journal plus : cardiology research and practice · 2026Article
- Sex differences in vascular endothelial function in predicting cardiovascular events in hypertensive patients.Internal and emergency medicine · 2026Article
- Persisting Sex Discrepancies in Short-Term Outcomes of Patients with ST-Segment Myocardial Infarction: Results of the ISACS-STEMI COVID-19 Registry.Journal of clinical medicine · 2026Article
- Diagnostic accuracy, treatment and prognosis of myocardial infarction: an 11-year follow-up of a community-based cohort of 0.5 million Chinese adults.BMJ public health · 2026Article
- The Influence of Gender on Long-Term Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction and the Association with Cardiac Left Ventricular Function.Diagnostics (Basel, Switzerland) · 2025Article
- Sex Differences in Mortality and Health Care Utilization After Dementia Diagnosis.JAMA neurology · 2025Article
- Trends in coronary artery disease mortality among hyperlipidemic patients: Geographic, gender, and racial insights from CDC WONDER data (1999-2020).International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Article
- Sex differences in outcomes in patients with acute myocardial infarction.BMC cardiovascular disorders · 2025Article
- Sex-based Differences in Complications Following Percutaneous Coronary Interventions.Current atherosclerosis reports · 2025Review
- Bridging Care Gaps for Older Women Undergoing Percutaneous Coronary Intervention.Interventional cardiology clinics · 2025Review
- Population and Co-Occurrence Characteristics of Diagnoses and Comorbidities in Coronary Artery Disease Patients: A Case Study from a Hospital in Guangxi, China.Bioengineering (Basel, Switzerland) · 2024Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundStudies of sex differences in long-term mortality after acute myocardial infarction have reported mixed results. A systematic review is needed to characterize what is known about sex differences in long-term outcomes and to define gaps in knowledge. METHODS AND
resultsWe searched the Medline database from 1966 to December 2012 to identify all studies that provided sex-based comparisons of mortality after acute myocardial infarction. Only studies with at least 5 years of follow-up were reviewed. Of the 1877 identified abstracts, 52 studies met the inclusion criteria, of which 39 were included in this review. Most studies included fewer than one-third women. There was significant heterogeneity across studies in patient populations, methodology, and risk adjustment, which produced substantial variability in risk estimates. In general, most studies reported higher unadjusted mortality for women compared with men at both 5 and 10 years after acute myocardial infarction; however, many of the differences in mortality became attenuated after adjustment for age. Multivariable models varied between studies; however, most reported a further reduction in sex differences after adjustment for covariates other than age. Few studies examined sex-by-age interactions; however, several studies reported interactions between sex and treatment whereby women have similar mortality risk as men after revascularization.
conclusionsSex differences in long-term mortality after acute myocardial infarction are largely explained by differences in age, comorbidities, and treatment use between women and men. Future research should aim to clarify how these differences in risk factors and presentation contribute to the sex gap in mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.