SynthesisThe British journal of radiology2014
Meta-analysis of CT-guided transthoracic needle biopsy for the evaluation of the ground-glass opacity pulmonary lesions.
Synthesis in The British journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Robotic-assisted versus conventional CT-guided lung biopsy for pulmonary nodules: a systematic review and meta-analysis.Journal of robotic surgery · 2026Pooled it
- EarlyCDT Lung blood test for risk classification of solid pulmonary nodules: systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2022Pooled it
- Ultrasound identification and sonoanatomy of the inferior fascicle of the anterior talofibular ligament: a cadaveric study.Journal of ultrasound · 2026Article
- Patient specific characteristics and risk of iatrogenic pneumothorax after CT-guided biopsy of the lung parenchyma.European clinical respiratory journal · 2026Article
- [Clinical Application of Robotic Assisted Bronchoscopy in Peripheral Pulmonary Nodule Biopsy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024Review
- Article
- A narrative review of the clinical approach to subsolid pulmonary nodules.Annals of translational medicine · 2023Review
- Review
- Computed Tomography-guided Lung Biopsy: A Review of Techniques for Reducing the Incidence of Complications.Interventional radiology (Higashimatsuyama-shi (Japan) · 2021Review
- [Expert Consensus for Thermal Ablation of Pulmonary Subsolid Nodules (2021 Edition)].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2021Article
- Managing screening-detected subsolid nodules-the Asian perspective.Translational lung cancer research · 2021Review
- Managing of screening-detected sub-solid nodules-a European perspective.Translational lung cancer research · 2021Review
- Percutaneous computed tomography guided biopsy of sub-solid pulmonary nodules: differentiating solid from ground glass components at the time of biopsy.Clinical imaging · 2021Article
- GGO and minimally invasive adenocarcinomas: how to deal with?Journal of thoracic disease · 2018Article
- A Systematic Review and Meta-Analysis of C-Arm Cone-Beam CT-Guided Percutaneous Transthoracic Needle Biopsy of Lung Nodules.Polish journal of radiology · 2017Article
- CT-guided needle biopsy in the diagnosis of lung adenocarcinoma accompanied by extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: a rare combination.International journal of clinical and experimental pathology · 2015Article
- Predictive factors for a successful diagnostic bronchoscopy of ground-glass nodules.Annals of thoracic medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis meta-analysis is to determine the overall diagnostic yield of CT-guided transthoracic needle biopsy (TNB) of ground-glass opacity (GGO) lesions.
methodsA PubMed search was performed using "ground-glass opacity" crossed with "core biopsy" and "needle biopsy". Test performance characteristics with the use of forest plots, summary receiver operating characteristic curves and bivariate random effects models were summarized. Adverse events, if reported, were recorded.
resultsOur search identified 52 citations, of which 6 diagnostic studies evaluated 341 patients. Pooled specificity estimates were 0.94 [95% confidence interval (CI), 0.84-0.98] and sensitivity estimates were 0.92 (95% CI, 0.88-0.95), respectively. The positive likelihood ratio was 11.27 (95% CI, 4.2-30.6), the negative likelihood ratio was 0.1 (95% CI, 0.06-0.19), the diagnostic odds ratio was 131.38 (95% CI, 39.6-436.0) and the area under the curve was 0.97.
conclusionOur data suggest that the CT-guided TNB is likely to be a useful tool for tissue diagnosis and may serve as an alternative for further patient management with GGO lesions. However, considering the limited studies and patients included, large scale studies are needed to verify these findings. ADVANCES IN KNOWLEDGE: Some studies about CT-guided TNB of GGO lesions have been published, most have been small, single-institution case series. To our knowledge, our study is the first systematic analysis about CT-guided TNB of GGO lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.