ArticleBMC genomics2014
Characterization of the MLO gene family in Rosaceae and gene expression analysis in Malus domestica.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 107 citations in OpenAlex.
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- Genome-wide identification, evolution, and expression analysis ofFrontiers in plant science · 2023Article
- MLO Proteins from Tomato (Plants (Basel, Switzerland) · 2022Article
- CmPMRl and CmPMrs are responsible for resistance to powdery mildew caused by Podosphaera xanthii race 1 in Melon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- The mPlant biotechnology journal · 2022Article
- High-Quality Genome Assembly ofFrontiers in plant science · 2022Article
- Cyclic nucleotide gated channel genes (CNGCs) in Rosaceae: genome-wide annotation, evolution and the roles on Valsa canker resistance.Plant cell reports · 2021Article
- Analysis of allelic variants of RhMLO genes in rose and functional studies on susceptibility to powdery mildew related to clade V homologs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Evolution of the MLO gene families in octoploid strawberry (Fragaria ×ananassa) and progenitor diploid species identified potential genes for strawberry powdery mildew resistance.Horticulture research · 2021Article
- Genome-Wide Characterization of theFrontiers in plant science · 2021Article
- Identification of Candidate Susceptibility Genes toFrontiers in plant science · 2021Article
- Effect of FeTheScientificWorldJournal · 2021Article
- Genome-Wide Identification of Powdery Mildew Resistance in Common Bean (Frontiers in genetics · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPowdery mildew (PM) is a major fungal disease of thousands of plant species, including many cultivated Rosaceae. PM pathogenesis is associated with up-regulation of MLO genes during early stages of infection, causing down-regulation of plant defense pathways. Specific members of the MLO gene family act as PM-susceptibility genes, as their loss-of-function mutations grant durable and broad-spectrum resistance.
resultsWe carried out a genome-wide characterization of the MLO gene family in apple, peach and strawberry, and we isolated apricot MLO homologs through a PCR-approach. Evolutionary relationships between MLO homologs were studied and syntenic blocks constructed. Homologs that are candidates for being PM susceptibility genes were inferred by phylogenetic relationships with functionally characterized MLO genes and, in apple, by monitoring their expression following inoculation with the PM causal pathogen Podosphaera leucotricha.
conclusionsGenomic tools available for Rosaceae were exploited in order to characterize the MLO gene family. Candidate MLO susceptibility genes were identified. In follow-up studies it can be investigated whether silencing or a loss-of-function mutations in one or more of these candidate genes leads to PM resistance.
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