SynthesisBMJ clinical evidence2014
Tonsillitis.
Synthesis in BMJ clinical evidence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- The impact of social determinants of health on pediatric tonsillectomy.International journal of pediatric otorhinolaryngology · 2025Pooled it
- Short-Term Weight Gain after Tonsillectomy Does Not Lead to Overweight: A Systematic Review.Nutrients · 2024Pooled it
- Potential efficacy and safety of Xiyanping injection as adjuvant therapy in treatment of suppurative acute tonsillitis: a meta-analysis, trial sequential analysis, and certainty of evidence.Frontiers in pharmacology · 2024Pooled it
- Antibiotics for recurrent acute pharyngo-tonsillitis: systematic review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Pooled it
- Tonsillectomy Versus Watchful Waiting for Recurrent Throat Infection: A Systematic Review.Pediatrics · 2017Pooled it
- Echinacea can help with Azithromycin in prevention of recurrent tonsillitis in children.American journal of otolaryngologyTrial
- Comparative efficacy and safety of co-amoxiclav, cefpodoxime proxetil, and levofloxacin in patients with acute uncomplicated bacterial tonsillitis: A prospective, open-label, parallel group study.Journal of family medicine and primary care · 2024Article
- Double trouble: Necrotizing tonsillitis in the setting ofRadiology case reports · 2024Article
- Article
- Diagnostic performance of short noncontrast biparametric 3-T MRI for tonsillar infections: comparison with a full protocol including contrast-enhanced sequences.European radiology experimental · 2023Article
- Effect of the German tonsillitis guideline on indication for tonsil surgery in patients with recurrent acute tonsillitis: a population-based study.Scientific reports · 2023Article
- Imaging of pharyngeal pathology.The British journal of radiology · 2023Review
- Can Shear Wave Elastography Help Differentiate Acute Tonsillitis from Normal Tonsils in Pediatric Patients: A Prospective Preliminary Study.Children (Basel, Switzerland) · 2023Article
- Implementing criteria-led discharge for acute admissions to facilitate the elective recovery from COVID-19: an example in acute tonsillitis.BMJ open quality · 2023Article
- Drivers of respiratory health care demand in Acre state, Brazilian Amazon: a cross-sectional study.BMC public health · 2022Review
- Quality of Life Assessment for Tonsillar Infections and Their Treatment.Medicina (Kaunas, Lithuania) · 2022Article
- Characterization of Tonsil Microbiota and Their Effect on Adenovirus Reactivation in Tonsillectomy Samples.Microbiology spectrum · 2021Article
- Bilateral Tonsillitis With Peritonsillar Abscess.Cureus · 2021Article
- Quality of the Italian Websites for Parental Guidance on the Indications for Tonsillectomy in Children.International archives of otorhinolaryngology · 2021Article
- Influence of Childhood Adversity and Infection on Timing of Menarche in a Multiethnic Sample of Women.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe definition of severe recurrent throat infections is arbitrary, but recent criteria have defined severe tonsillitis as: five or more episodes of true tonsillitis a year; symptoms for at least 1 year; and episodes that are disabling and prevent normal functioning. Diagnosis of acute tonsillitis is clinical, and it can be difficult to distinguish viral from bacterial infections. Rapid antigen testing has a very low sensitivity in the diagnosis of bacterial tonsillitis, but more accurate tests take longer to deliver results. Bacteria are cultured from few people with tonsillitis. Other causes include infectious mononucleosis from Epstein-Barr virus infection, cytomegalovirus, toxoplasmosis, HIV, hepatitis A, and rubella. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of tonsillectomy in children and adults with acute recurrent or chronic throat infections? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 15 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review, we present information relating to the effectiveness and safety of the following interventions: cold-steel tonsillectomy and diathermy tonsillectomy.
Indexed as
Identifiers
25051184PMC4106232W4300036886What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.