ArticleTranslational psychiatry2014
The association between family history of mental disorders and general cognitive ability.
Article in Translational psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Cognitive reserve in non-affective first-episode psychosis: contributions of polygenic scores, early clinical features, and environment.Psychological medicine · 2026Article
- Progression of Transdiagnostic Stages From Childhood to Young Adulthood.JAMA psychiatry · 2025Article
- Article
- Predicting adolescent psychopathology from early life factors: A machine learning tutorial.Global epidemiology · 2024Article
- Mental health literacy and help-seeking behaviour among Egyptian undergraduates: a cross-sectional national study.BMC psychiatry · 2024Article
- Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks.Translational psychiatry · 2023Article
- Preoperative mental illness and postoperative atrial fibrillation in cardiac surgery patients: Identifying a vulnerable population.Journal of clinical and translational science · 2023Article
- School performance and later diagnoses of nonaffective psychoses, bipolar disorder, and depression.Acta psychiatrica Scandinavica · 2022Article
- Psychiatric disorders and associated risk factors in a sample of adolescents in Gaborone, Botswana: a cross-sectional study.BMC pediatrics · 2022Article
- Article
- COVID-19-Induced Anxiety and Associated Factors Among Urban Residents in West Shewa Zone, Central Ethiopia, 2020.Psychology research and behavior management · 2021Article
- Association of Mental Disorder in Childhood and Adolescence With Subsequent Educational Achievement.JAMA psychiatry · 2020Article
- Family Features of Social Withdrawal Syndrome (Hikikomori).Frontiers in psychiatry · 2020Article
- White matter microstructure mediates the association between physical fitness and cognition in healthy, young adults.Scientific reports · 2019Article
- Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?Schizophrenia research. Cognition · 2017Article
- Characterizing neurocognitive impairment in young people with major depression: state, trait, or scar?Brain and behavior · 2016Review
- Polygenic Risk of Schizophrenia and Cognition in a Population-Based Survey of Older Adults.Schizophrenia bulletin · 2016Article
- The Association between Infections and General Cognitive Ability in Young Men - A Nationwide Study.PloS one · 2015Article
- Role of TNF-α -308G/A Polymorphism in Bipolar Disorder and its Relationship with Clinical and Demographic Variables.Innovations in clinical neuroscienceArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is an emerging literature linking cognitive ability with a wide range of psychiatric disorders. These findings have led to the hypothesis that diminished 'cognitive reserve' is a causal risk factor for psychiatric disorders. However, it is also feasible that a family history of mental disorders may confound this relationship, by contributing to both a slight impairment in cognitive ability, and an increased risk of psychiatric disorder. On the basis of a large, population-based sample of young adult male conscripts (n=160 608), we examined whether the presence of a family history of a range of mental disorders was associated with cognitive ability, as tested by the Børge Priens Prøve. In those with no individual-level history of mental disorder, a family-level history of a mental disorder was associated with a slight reduction in cognitive ability. In general, this pattern was found regardless of the nature of the psychiatric disorder in the family. Our study suggests that shared familial factors may underpin both cognitive ability and the risk of a wide range of psychiatric disorders. Convergent evidence from epidemiology and genetics suggests that shared genetic factors underpin an unexpectedly diverse range of psychiatric disorders. On the basis of the findings of the current study, we speculate that these same shared genetic factors also contribute to general cognitive ability.
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