Evidence map›Paper›PMID 25050961›Full record

ArticleCurrent biology : CB2014

Docking interactions: cell-cycle regulation and beyond.

Mardo Kõivomägi, Jan M Skotheim

Open access · bronzeAbstract readComment
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Multisite phosphorylation code of CDK.Nature structural & molecular biology · 2019
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mardo KõivomägiDepartment of Biology, Stanford University, Stanford, CA 94305, USA.
Jan M SkotheimDepartment of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: Skotheim@stanford.edu.
Stanford University · US

Funding

TRAINING & OUTREACH COREP50GM107615 · NIGMS · STANFORD UNIVERSITY · PI COVERT, MARKUS W · 2013 to 2017
$10.9M
Mechanisms of restriction point response to dynamic growth factor signalsR01GM092925 · NIGMS · STANFORD UNIVERSITY · PI SKOTHEIM, JAN M · 2010 to 2018
$2.8M
NIGMS NIH HHS P50 GM107615NIGMS NIH HHS R01 GM092925
6 · The paper itself

Abstract

In budding yeast, the mating pathway activates Far1 to inhibit G1 cyclins in complex with the cyclin-dependent kinase (Cln-Cdk). Yet, the molecular mechanism has remained largely unclear for over 20 years. A recent report helps shed light on this regulation.

Indexed as

G1 PhaseGene Expression Regulation, FungalSignal TransductionCyclin-Dependent Kinase Inhibitor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCyclin-Dependent Kinase Inhibitor ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID25050961
PMCPMC6771416
OpenAlexW2087489667

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.