Evidence map›Paper›PMID 25050872›Full record

Trial reportPalliative & supportive care2015

A cognitive-existential intervention to improve existential and global quality of life in cancer patients: A pilot study.

Pierre Gagnon, Lise Fillion, Marie-Anik Robitaille, Michèle Girard, François Tardif, Jean-Philippe Cochrane, Joanie Le Moignan Moreau, William Breitbart

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Palliative & supportive care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01141933 (Creating Meaning Following Cancer), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01141933 naunknown statusnot on this map

Creating Meaning Following Cancer: An Cognitive-existential Intervention to Improve Existential and Global Quality of Life

TypeinterventionalSponsorCHU de Quebec-Universite LavalRan2009 to 2018Enrolled513ConditionsNon-metastatic Cancer, Adjustment DisorderArmsCognitive-existential intervention, Usual care
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pierre GagnonFaculty of Pharmacy,Laval University,Québec City,Quebec,Canada.
Lise FillionÉquipe de recherche Michel-Sarrazin en Oncologie psychosociale et Soins palliatifs,Research Center,Oncology Division,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
Marie-Anik RobitailleÉquipe de recherche Michel-Sarrazin en Oncologie psychosociale et Soins palliatifs,Research Center,Oncology Division,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
Michèle GirardDepartment of Palliative Care,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
François TardifÉquipe de recherche Michel-Sarrazin en Oncologie psychosociale et Soins palliatifs,Research Center,Oncology Division,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
Jean-Philippe CochraneÉquipe de recherche Michel-Sarrazin en Oncologie psychosociale et Soins palliatifs,Research Center,Oncology Division,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
Joanie Le Moignan MoreauÉquipe de recherche Michel-Sarrazin en Oncologie psychosociale et Soins palliatifs,Research Center,Oncology Division,CHU de Québec - L'Hôtel-Dieu de Québec,Québec City,Quebec,Canada.
William BreitbartDepartment of Psychiatry and Behavioral Sciences,Memorial Sloan Kettering Cancer Center,New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
CIHRNCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveWe developed a specific cognitive-existential intervention to improve existential distress in nonmetastatic cancer patients. The present study reports the feasibility of implementing and evaluating this intervention, which involved 12 weekly sessions in both individual and group formats, and explores the efficacy of the intervention on existential and global quality of life (QoL) measures.

methodSome 33 nonmetastatic cancer patients were randomized between the group intervention, the individual intervention, and the usual condition of care. Evaluation of the intervention on the existential and global QoL of patients was performed using the existential well-being subscale and the global scale of the McGill Quality of Life (MQoL) Questionnaire.

resultsAll participants agreed that their participation in the program helped them deal with their illness and their personal life. Some 88.9% of participants agreed that this program should be proposed for all cancer patients, and 94.5% agreed that this intervention helped them to reflect on the meaning of their life. At post-intervention, both existential and psychological QoL improved in the group intervention versus usual care (p = 0.086 and 0.077, respectively). At the three-month follow-up, global and psychological QoL improved in the individual intervention versus usual care (p = 0.056 and 0.047, respectively). SIGNIFICANCE OF

resultsThis pilot study confirms the relevance of the intervention and the feasibility of the recruitment and randomization processes. The data strongly suggest a potential efficacy of the intervention for existential and global quality of life, which will have to be confirmed in a larger study.

Indexed as

Quality of LifeAdultAgedCognitive Behavioral TherapyExistentialismFemaleHumansMaleMiddle AgedNeoplasmsPalliative CarePilot ProjectsQuebecSurveys and QuestionnairesCancerCognitive–existential interventionExistentialQuality of life

Identifiers

PMID25050872
PMCPMC5485259

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.