Evidence map›Paper›PMID 25050758›Full record

ArticleBiomatter2014

Magnetic force microscopy: quantitative issues in biomaterials.

Daniele Passeri, Chunhua Dong, Melania Reggente, Livia Angeloni, Mario Barteri, Francesca A Scaramuzzo, Francesca De Angelis, Fiorenzo Marinelli, Flavia Antonelli, Federica Rinaldi and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Biomatter, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Indirect magnetic force microscopy.Nanoscale advances · 2019
    Article
  11. Article
  12. Magnetic mapping of iron in rodent spleen.Nanomedicine : nanotechnology, biology, and medicine · 2017
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 5 countries.

Daniele PasseriDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy.
Chunhua DongDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy; Department of Physics; University of Rome Sapienza; Rome, Italy.
Melania ReggenteDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy.
Livia AngeloniDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy; Lab. for Biomaterials and Bioengineering (CRC-I); Department Min-Met-Materials Eng. & University Hospital Research Center; Laval University; Quebec City, Canada.
Mario BarteriDepartment of Chemistry; University of Rome Sapienza; Rome, Italy.
Francesca A ScaramuzzoDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy.
Francesca De AngelisDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics; University of Rome Sapienza; Rome, Italy; Center for Life Nano Science@Sapienza; Istituto Italiano di Tecnologia; Rome, Italy.
Fiorenzo MarinelliIstituto di Genetica Molecolare; CNR; Istituto Rizzoli; Bologna, Italy.
Flavia AntonelliDepartment of Chemistry; University of Rome Sapienza; Rome, Italy.
Federica RinaldiDepartment of Drug Chemistry and Technologies; University of Rome Sapienza; Rome, Italy.
Carlotta MarianecciDepartment of Drug Chemistry and Technologies; University of Rome Sapienza; Rome, Italy.
Maria CarafaDepartment of Drug Chemistry and Technologies; University of Rome Sapienza; Rome, Italy.
Angela SorboDepartment of Food Safety and Veterinary Public Health; Istituto Superiore di Sanità; Rome, Italy.
Daniela SordiDelft University of Technology; Biotechnology Department; Biocatalysis and Organic Chemistry Section; Delft, The Netherlands.
Isabel Wce ArendsDelft University of Technology; Biotechnology Department; Biocatalysis and Organic Chemistry Section; Delft, The Netherlands.
Marco RossiDepartment of Basic and Applied Sciences for Engineering; University of Rome Sapienza; Rome, Italy; Centro di Ricerca per le Nanotecnologie Applicate all'Ingegneria della Sapienza (CNIS); University of Rome Sapienza; Rome, Italy.
Sapienza University of Rome · ITBiocat · ESIstituto di Genetica Molecolare · ITIstituto Superiore di Sanità · ITItalian Institute of Technology · ITUniversité Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic force microscopy (MFM) is an atomic force microscopy (AFM) based technique in which an AFM tip with a magnetic coating is used to probe local magnetic fields with the typical AFM spatial resolution, thus allowing one to acquire images reflecting the local magnetic properties of the samples at the nanoscale. Being a well established tool for the characterization of magnetic recording media, superconductors and magnetic nanomaterials, MFM is finding constantly increasing application in the study of magnetic properties of materials and systems of biological and biomedical interest. After reviewing these latter applications, three case studies are presented in which MFM is used to characterize: (i) magnetoferritin synthesized using apoferritin as molecular reactor; (ii) magnetic nanoparticles loaded niosomes to be used as nanocarriers for drug delivery; (iii) leukemic cells labeled using folic acid-coated core-shell superparamagnetic nanoparticles in order to exploit the presence of folate receptors on the cell membrane surface. In these examples, MFM data are quantitatively analyzed evidencing the limits of the simple analytical models currently used. Provided that suitable models are used to simulate the MFM response, MFM can be used to evaluate the magnetic momentum of the core of magnetoferritin, the iron entrapment efficiency in single vesicles, or the uptake of magnetic nanoparticles into cells.

Indexed as

ApoferritinsCell Line, TumorCoated Materials, BiocompatibleDrug CarriersFolic AcidHumansIronMagnetic FieldsMicroscopy, Atomic ForceModels, TheoreticalNanoparticlesOxidesParticle SizePolyethylene GlycolsPolylysineSurface PropertiesApoferritinsCoated Materials, BiocompatibleDrug CarriersFolic AcidIronmagnetoferritin(O-methylpoly(ethylene glycol)-O'-succinyl)-N-epsilon-poly(L-lysine)OxidesPolyethylene GlycolsPolylysinecell labellingdrug deliveryferritinfolic acid receptorleukemia cellmagnetic force microscopymagnetic nanoparticlemagnetoferritinniosomevesicle

Identifiers

PMID25050758
PMCPMC4145005
OpenAlexW2114370982

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.